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The carotenoid transfer between 2 proteins

08-Sep-2017

Specialists from the biological faculty of Moscow State University have studied the way the photoactive orange carotenoid protein (OCP) exchanges carotenoid with proteins of similar structure. The discovery will boost the development of OCP-based antioxidant drugs aimed at protecting healthy ...

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Peptide complex formed in the brain is responsible for Alzheimer's disease

17-Jul-2017

Members of the Faculty of Fundamental Medicine at the Lomonosov Moscow State University have determined the structure of a peptide complex, formed in the brain at the early stages of Alzheimer's disease progression. The research results will contribute to the rational design of compounds, capable ...

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New femto-camera with quadrillion fractions of a second resolution

22-Jun-2017

Researchers from ITMO University have built a setup for recording holograms of tiny objects like living cells with a femtosecond speed. The new method allows one to reconstruct phase topography of a studied sample according to deformations that emerge in a laser pulse when it passes through the ...

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Nanosized silicon heater and thermometer combined to fight cancer

06-Jun-2017

Russian physicists from ITMO University have found out that spherical silicon nanoparticles can be effectively heated up, and simultaneously emit light depending on their temperature. According to the scientists, these properties coupled with a good biocompatibility will allow usage of the ...

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New radiopharmaceutical based on DARPin scaffold for cancer diagnosis

99Tc-artificial protein chelate complex ready for preclinical trials

01-Jun-2017

A radiopharmaceutical for advanced identification of cancer, labeled with the technetium-99 isotope, is ready for the preclinical-phase trial. Scientists from Tomsk Polytechnic University, Tomsk Research Institute of Oncology and the Institute of Biorganic Chemistry of the Russian Academy of ...

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Biophysicists say iodine is the solution of biomolecule structures

18-May-2017

An international team including researchers from MIPT has shown that iodide phasing--a long-established method in structural biology--is universally applicable to membrane protein structure determination. Knowledge of these structures enables a molecular-level understanding of the workings of ...

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One step closer to crack the mystery of bacterial adaptation to antibiotics

12-Apr-2017

An international team including researchers from MIPT's Laboratory for Advanced Studies of Membrane Proteins have proposed an explanation of the way bacteria process external signals. By identifying the detailed structure of the protein complex used by bacteria, the scientists gained insights ...

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Nanozymes - efficient antidote against pesticides

09-Mar-2017

Members of the Faculty of Chemistry of the Lomonosov Moscow State University have developed novel nanosized agents - nanozymes, which could be used as efficient protective and antidote modalities against the impact of neurotoxic organophosphorous compounds: pesticides and chemical warfare ...

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Biophysicists propose new approach for membrane protein crystallization

08-Mar-2017

A team of scientists from the Laboratory for Advanced Studies of Membrane Proteins at MIPT, Research Center Jülich (Germany), and Institut de Biologie Structurale (France) have developed a new approach to membrane protein crystallization. For the first time, the scientists showed that membrane ...

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Supercrystals with new architecture can enhance drug synthesis

24-May-2016

Scientists from ITMO University and Trinity College have designed an optically active nanosized supercrystal whose novel architecture can help separate organic molecules, thus considerably facilitating the technology of drug synthesis. The structure of the new supercrystal is similar to a helix ...

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