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484 Current news from canadarss
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How a key cancer mutation activates telomerase, the ‘anti-aging enzyme’ that makes tumour cells immortal
Canadian scientists have achieved a first in the study of telomerase, an essential enzyme implicated in aging and cancer. In the journal Molecular Cell, scientists from Université de Montréal used advanced microscopy techniques to see single molecules of telomerase in living cells. A flaw in the ...
Scientists can now edit multiple genome fragments at a time
Toronto scientists can now edit multiple sites in the genome at the same time to learn how different DNA stretches co-operate in health and disease. CRISPR-based DNA editing has revolutionized the study of the human genome by allowing precise deletion of any human gene to glean insights into its ...
Boon for the making of pharmaceuticals and electronics
Macrocycles are molecules made of large rings of atoms. Despite being relatively big and flexible, the molecules don't always stay "floppy" -- they can actually lock themselves into specific shapes and geometries. In manufacturing, controlling the three-dimensional shapes of macrocycles is ...
A team of researchers at McMaster University has developed a self-cleaning surface that can repel all forms of bacteria, preventing the transfer of antibiotic-resistant superbugs and other dangerous bacteria in settings ranging from hospitals to kitchens. The new plastic surface - a treated form ...
New research sets the stage for new therapeutic strategies for Alzheimer's disease
Research shows that white blood cells in the human brain are regulated by a protein called CD33--a finding with important implications in the fight against Alzheimer's disease, according to a new study by University of Alberta chemists. "Immune cells in the brain, called microglia, play a ...
New protein targets for drug development against prostate cancer
Mining the rich uncharted territory of the genome or genetic material of a cancer cell has yielded gold for Princess Margaret scientists: new protein targets for drug development against prostate cancer. Using state-of-the-art, whole-genome sequencing technologies on prostate tumour samples, ...
Dr Christopher E. Rudd, a researcher at the Centre de recherche de l'Hôpital Maisonneuve-Rosemont (CR-HMR) and Université de Montréal, has discovered a new cell therapy approach that boosts the immune response of T lymphocytes to malignant tumours. "Our work has identified a new T-cell protein ...
Scientists demonstrate flaws in protein detection tools, and outline a solution
A new study points to the need for better antibody validation, and outlines a process that other labs can use to make sure the antibodies they work with function properly. Antibodies are used in laboratories and clinics to study proteins, which are the biomolecules that translate information from ...
Two short strings of amino acids could pave the way to new treatments for Alzheimer's disease
Two years after discovering a way to neutralize a rogue protein linked to Alzheimer's disease, University of Alberta Distinguished University Professor and neurologist Jack Jhamandas has found a new piece of the Alzheimer's puzzle, bringing him closer to a treatment for the disease. In a study ...
McMaster researchers have developed a novel new gel made entirely from bacteria-killing viruses. The anti-bacterial gel, which can be targeted to attack specific forms of bacteria, holds promise for numerous beneficial applications in medicine and environmental protection. Among many ...