Induced Pluripotent Stem Cells

News Induced Pluripotent Stem Cells

• Lab grown ‘brains’ successfully model disease
  

  Scientists were able to model a developmental disorder called neuronal heterotopia which can lead to intellectual disability and epilepsy. They used a model of brain development called brain organoids where human cells organize themselves in the petri dish into brain-like structures. Brain organoids more

• Deciphering diabetes with "game-changing" human blood vessels from stem cells
  

  Changes in blood vessels are the major cause of death and morbidity in diabetes. For the first time, scientists managed to grow perfect human blood vessels as organoids in a petri dish. This breakthrough engineering technology dramatically advances research of vascular dysfunction in diseases like d more

• System that reduces neurodegeneration in Huntington’s disease
  

  The neuroscientist Dr David Vilchez and his team at CECAD, the University of Cologne’s Cluster of Excellence for Aging Research, have made an important step towards understanding the mechanisms that cause the neurodegenerative disorder Huntington’s disease. Particularly, they identified a system blo more

Events Induced Pluripotent Stem Cells

Publications Induced Pluripotent Stem Cells

• Retraction: Matrix Metalloproteinase-3 in Odontoblastic Cells Derived from Ips Cells: Unique Proliferation Response as Odontoblastic Cells Derived from ES Cells

  by The PLOS ONE Editors more

• [In Depth] iPS cell therapy reported safe

  Japanese researchers reported this week that the first trial of induced pluripotent stem (iPS) cells in a human has proved safe and effective in halting the progression of age-related macular degeneration (AMD), though there was minimal improvement in vision. AMD is the leading cause of vision loss more

• Highly efficient biallelic genome editing of human ES/iPS cells using a CRISPR/Cas9 or TALEN system

  Abstract Genome editing research of human ES/iPS cells has been accelerated by clustered regularly interspaced short palindromic repeats/CRISPR-associated 9 (CRISPR/Cas9) and transcription activator-like effector nucleases (TALEN) technologies. However, the efficiency of biallelic genetic engineeri more