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Gemzar

News Gemzar

  • U.S. District Court Rules Against Lilly Regarding Gemzar Patent

    Eli Lilly and Company announced that the U.S. District Court for the Eastern District of Michigan has granted a motion by Sun Pharmaceuticals for partial summary judgment. The Court's ruling invalidates Lilly's '826 patent, or method-of-use patent, for Gemzar((R)) (gemcitabine HCl for injection) wh more

  • Cytotoxic therapies to feel sting of generics

    Cytotoxic therapy, or chemotherapy as it is commonly known, has been the cornerstone of cancer treatment for many years and involves the use of drugs that are toxic to all cells – including those that are perfectly healthy. Whilst relatively effective, this leads to the unpleasant side effects commo more

  • Analysis of R&D portfolio management

    At the core of portfolio management lies the need to identify and prioritise the most profitable products/projects in the R&D pipeline with the aim of maximising return on investment. For the pharmaceutical industry, the difficulty of quantifying the uncertainties associated with product development more

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Publications Gemzar

  • Discovery of antimicrobial ribonucleotide reductase inhibitors by screening in microwell format [Biochemistry]

    Ribonucleotide reductase (RNR) catalyzes reduction of the four different ribonucleotides to their corresponding deoxyribonucleotides and is the rate-limiting enzyme in DNA synthesis. RNR is a well-established target for the antiproliferative drugs Gemzar and Hydrea, for antisense therapy, and in com more

  • Patent watch

    Patent watch Nature Reviews Drug Discovery 9, 672 (2010). doi:10.1038/nrd3273 Author: Charlotte Harrison Sun Pharmaceuticals wins Gemzar patent disputeGenerics manufacturer Sun Pharmaceuticals has succeeded in having a patent that protects Eli Lilly's anticancer drug Gemzar (gemcitabine) i more

Definition

Gemcitabine

Gemcitabine Gemcitabine is a nucleoside analog used as chemotherapy . It is marketed as Gemzar® by Eli Lilly and Company . Pharmacology Chemically gemcitabine is a nucleoside analog in which the hydrogens on the 2' carbons of deoxycytidine a ... more

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