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Degenerative Disorder

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  • Stem cell research delivers new points of attack against Parkinson’s disease

    In a seven-year research effort, an international team of scientists has clarified the cause for certain genetic forms of Parkinson’s disease, and has identified potential pharmacological treatments. The interdisciplinary research team, led by Prof. Rejko Krüger, of the Luxembourg Centre for Systems more

  • New method reveals how the Parkinson's disease protein damages cell membranes

    In sufferers of Parkinson's disease, clumps of α-synuclein (alpha-synuclein), sometimes known as the 'Parkinson's protein', are found in the brain. These destroy cell membranes, eventually resulting in cell death. Now, a new method developed at Chalmers University of Technology, Sweden, reveals how more

  • Cleaning craze in the brain

    Synapses consist of hundreds of different proteins. For correct transmission of brain signals, their building blocks must constantly be checked for functionality and replaced by new ones. A team of researchers from the Leibniz Institute of Neurobiology Magdeburg, the German Centre for Neurodegenerat more

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Fly models of Parkinson’s disease point way to new therapies

Celardi et al. "Mitofusin-mediated ER stress triggers neurodegeneration in pink1/parkin models of Parkinson’s disease" Cell Death and Disease (2016). doi:10.1038/cddis.2016.173 more

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Deuterating fatty acids to treat diseases

Maksim Fomich is currently looking into creating deuterated polyunsaturated fatty acid compounds, with a view to using them to potentially treat a range of diseases. Here, he shows the premise behind his research. A description of his research can be read via the link on the right side. more

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