For more than two decades IBA Lifesciences develops
and provides innovative solutions for your life science
applications. Our portfolio includes tools for Cell Selection
& Expansion, Protein Production & Assays as well
as Custom Oligos & Predefined DNA/RNA.
Cell selection & expansion
Fab-TACS® technology ensures automated cell selection
directly from whole blood employing IBA’s design awardwinning FABian® device. Customized protocols
depending on the cell type, the sample volume, and the
intended yield allow for convenient fully automatic cell
isolation. Strep-tagged Fab fragments (Fab-Streps) reversibly capture and release the target cells during
the selection process. This delivers label-free, non-activated target cells in a standardized manner of highly reproducible quality. Isolated cells are suitable
for all further immunological or cell biological investigations, including cell-based diagnostics or assays, e.g. pharmacological analysis of drug levels in the isolated cell fraction. For convenient manual cell selection we offer Fab-TACS® Gravity columns. For T cell stimulation, we offer completely novel reversible reagents, the Streptamers® for cell expansion, which provide unique flexibility for cell research.
Protein production & assays
The Strep-tag® technology is IBA’s proprietary and
versatile protein purification, detection, and immobilization
platform. It is one of the most widely used systems for affinity purification, providing exceptionally pure proteins. Recently the third generation of the Strep-tag® system was launched, based on the new Strep-Tactin®XT and Twin-Strep-tag®. Strep-Tactin®XT is a further developed Strep-Tactin® with extra high affinity to Twin-Strep-tag®, which now enables the use of the Strep-tag® technology in applications where extra tight binding is a requirement. With this feature, the third generation Strep-tag® technology now enters the field of assay development and screening, opening new possibilities in the pharmaceutical and biotech sector for, e.g. screening of new diagnostic targets and the development of diagnostic assays.
Custom oligos & predefined DNA/RNA
IBA’s nucleic acid division focuses on specialized nucleic
acid custom services. The tailor-made DNA and RNA oligonucleotides, including modified and labelled nucleic acids, require particular care in synthesis and are of the highest quality. Applications can be found in e.g. real-time PCR, FRET, gene silencing studies, immobilization,
FCCS, or high-resolution microscopy. The innovative Click Chemistry enables additional dye combinations with unsurpassed labelling densities. More than 200 fluorescent labels and more than 80 modifications are available. With our expertise, we can also produce custom DNA and RNA aptamers according to your individual specifications.