Atrophy

News Atrophy

• Rentschler Biopharma joins forces with Ikarovec to accelerate novel gene therapies
  

  Rentschler Biopharma SE and Ikarovec, which is developing novel multicistronic gene therapies to treat major ophthalmic indications, announced that the two companies have entered into a collaboration. Under the agreement, Rentschler Biopharma’s ATMP site in Stevenage, UK, will support the bioprocess more

• Poor heart health predicts premature brain ageing
  

  By estimating people’s brain age from MRI scans using machine learning, a team led by UCL researchers has identified multiple risk factors for a prematurely ageing brain. They found that worse cardiovascular health at age 36 predicted a higher brain age later in life, while men also tended to have o more

• Using mRNA delivery to improve muscle strength
  

  Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications. It may be only more