Alzheimer's Disease

Companies Alzheimer's Disease

SunRegen Healthcare AG, Switzerland

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Alzheon, Inc., USA

Alzheon, Inc. is committed to developing innovative medicines by directly addressing the underlying pathology of devastating neurodegenerative disorders. Our lead Alzheimer's clinical candidate, ALZ-801, is an oral small molecule prodrug of tramiprosate that fully blocks formation of neurotoxic solu more

Asceneuron SA, Switzerland

Asceneuron is a clinical stage biotech company focused on the development of orally bioavailable therapeutics for debilitating neurodegenerative disorders with high unmet medical need. The pipeline reflects our ambition to develop treatments for a wide a range of neurodegenerative diseases including more

News Alzheimer's Disease

• Poorly insulated nerve cells promote Alzheimer’s disease in old age
  

  Alzheimer’s disease, an irreversible form of dementia, is considered the world’s most common neurodegenerative disease. The prime risk factor for Alzheimer’s is age, although it remains unclear why. It is known that the insulating layer around nerve cells in the brain, named myelin, degenerates with more

• Schizophrenia drug as new therapy against dementia
  

  MHH neurophysiologist demonstrates the effect of the antipsychotic amisulpride on harmful protein deposits in nerve cells of the brain. A clinical trial will investigate the drug's efficacy in dementia patients. A common feature of many neurodegenerative diseases are pathological protein deposits in more

• Ultra-long protein fibrils give clues on dementia risk
  

  During the course of Alzheimer's disease, protein fibrils appear in the spinal fluid of affected individuals. Empa researchers, together with the Department of Neurology at the Cantonal Hospital in St. Gallen, have now visualized the wide spectrum of protein aggregates from oligomers, protofibrils t more

Videos Alzheimer's Disease

Chaperones - folding helpers in the cell

Nothing works without the correct form: For most proteins, there are millions of ways in which these molecules, composed of long chains of amino acids, can be folded - but only one way is the right one. Researchers in the department "Cellular Biochemistry" at the Max Planck Institute for Biochem ... more

White papers Alzheimer's Disease

• Novel aggregation-specific fluorogen monitors prefibrillar protein aggregation by fluorescence polarisation (FP)
  

  Highly ordered protein aggregates, termed amyloid fibrils, are associated with a broad range of diseases, many of which are neurodegenerative more