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2.242 Aktuelle Fachpublikationen zum Thema Flüssigchromatographie


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Syzygium cumini seed exhibits antidiabetic potential via multiple pathways involving inhibition of α‐glucosidase, DPP‐IV, glycation, and ameliorating glucose uptake in L6 cell lines

21.09.2017 | Hari Priya Syama, Karthika Bahulayan Arun, George Sinumol, Rajendran Dhanya, Sasidharan Suseela Anusree, P. Nisha, L ..., Journal of Food Processing and Preservation, 2017

Abstract The present study evaluated antidiabetic potential of fractions of Syzygium cumini seeds and identified major polyphenolic compounds in them. Potential α‐glucosidase and α‐amylase inhibition (IC50 1.7 and 7.62μg/ml, respectively) was demonstrated by 70% methanol fraction while ...


A Bis-benzopyrroloisoquinoline Alkaloid Incorporating a Cyclobutane Core and a Chlorophenanthroindolizidine Alkaloid with Cytotoxic Activity from Ficus fistulosa var. tengerensis

19.09.2017 | Amjad Ayad Qatran Al-Khdhairawi; Premanand Krishnan; Chun-Wai Mai; Felicia Fei-Lei Chung; Chee-Onn Leong; Kien-Thai ..., Journal of Natural Products, 2017

Tengerensine (1), isolated as a racemate and constituted from a pair of bis-benzopyrroloisoquinoline enantiomers, and tengechlorenine (2), purified as a scalemic mixture and constituted from a pair of chlorinated phenanthroindolizidine enantiomers, were isolated from the leaves of Ficus fistulosa ...


D-amino acid substitution enhances the stability of antimicrobial peptide polybia-CP

18.09.2017 | Jia F, Wang J, Peng J, et al., Acta Biochimica et Biophysica Sinica, 2017

Abstract With the increasing emergence of resistant microbes toward conventional antimicrobial agents, there is an urgent need for the development of antimicrobial agents with novel action mode. Antimicrobial peptides (AMPs) are believed to be one kind of ideal alternatives. However, AMPs can be ...


Novel Insights into the Inhibitory Effect and Mechanism of Proanthocyanidins from Pyracantha fortuneana Fruit on α‐Glucosidase

14.09.2017 | Mankun Wei, Wei‐Ming Chai, Qin Yang, Rui Wang, Yiyuan Peng, Journal of Food Science, 2017

Abstract Proanthocyanidins were extracted from Pyracantha fortuneana fruit (PFF), and their structures were investigated through 13C nuclear magnetic resonance (13C NMR), high performance liquid chromatography (HPLC) and high resolution mass spectrometry (HRMS). The results showed that these ...


Simulated gastrointestinal digestion and in vitro colonic fermentation of date (Phoenix dactylifera L.) seed polyphenols

14.09.2017 | Sameera Sirisena, Said Ajlouni, Ken Ng, International Journal of Food Science & Technology, 2017

Summary Date seeds are a by‐product of date fruit industry and a rich source of polyphenols. In this study, invitro bioaccessibility and colonic fermentation of major polyphenols from date seed powder (DSP) and DSP‐fortified yoghurt (DSPY) were investigated using HPLC. Catechin, epicatechin ...


Synthesis, Quality Control and Bio‐evaluation of 99mTc‐cyclophosphamide

08.09.2017 | Tanveer Hussain Bokhari, Samina Roohi, Saira Hina, Muhammad Usman Akbar, Muhammad Sohaib, Munawar Iqbal, Chemical Biology & Drug Design, 2017

Abstract Cancer is found to be the leading cause of death worldwide characterized by uncontrolled cell division. Nuclear medicines imaging by using radiopharmaceuticals have pronounced potential for the diagnosis and treatment of cancers. Cyclophosphamide (CPH) is an antineoplastic drug which ...


Mannich base approach to 5-methoxyisatin 3-(4-isopropylphenyl)hydrazone: A water-soluble prodrug for a multitarget inhibition of cholinesterases, beta-amyloid fibrillization and oligomer-induced cytotoxicity

03.09.2017 | Author(s): Leonardo Pisani, Annalisa De Palma, Nicola Giangregorio, Daniela V. Miniero, Paolo Pesce, Orazi ..., European Journal of Pharmaceutical Science, 2017

Publication date: 15 November 2017 Source:European Journal of Pharmaceutical Sciences, Volume 109 Author(s): Leonardo Pisani, Annalisa De Palma, Nicola Giangregorio, Daniela V. Miniero, Paolo Pesce, Orazio Nicolotti, Francesco Campagna, Cosimo D. Altomare, Marco Catto ...


A novel red pigment from marine Arthrobacter sp. G20 with specific anticancer activity

01.09.2017 | Simindokht Afra, Ali Makhdoumi, Maryam M. Matin, Javad Feizy, Journal of Applied Microbiology, 2017

Abstract Aims Bacterial pigments are promising compounds in the prevention and treatment of various cancers. In the current study, the antioxidant, cytotoxic, and antimicrobial effects of a red pigment obtained from a marine bacterial strain were investigated. Methods and ...


Stability of an Aqueous Extract of Larrea divaricata Cav. during a Simulated Digestion Process

31.08.2017 | María Rosario Alonso, Ignacio Peralta, Demian Monti, Renzo Martino, Claudia Anesini, Phytotherapy Research, 2017

Larrea divaricata Cav. (Zygophyllaceae) is a South American plant widely distributed in Argentina that is used in folk medicine to treat inflammatory diseases. The aqueous extract is known to have well‐documented biological activities such as antitumour, immunomodulatory, antimicrobial, ...


Marine Drugs, Vol. 15, Pages 278: HPLC-HRMS Quantification of the Ichthyotoxin Karmitoxin from Karlodinium armiger

31.08.2017 | Andersen, Aaron John Christian; de Medeiros, Lívia Soman; Binzer, Sofie Bjørnholt; Rasmussen, Silas Anselm; Hansen, ..., Marine Drugs, 2017

Marine Drugs, Vol. 15, Pages 278: HPLC-HRMS Quantification of the Ichthyotoxin Karmitoxin from Karlodinium armiger Marine Drugs doi: 10.3390/md15090278 Authors: Aaron Andersen Lívia de Medeiros Sofie Binzer Silas Rasmussen Per Hansen Kristian Nielsen Kevin Jørgensen Thomas ...


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