29.06.2018 | Carl Willers; Hanna Iderberg; Mette Axelsen; Tobias Dahlström; Bettina Julin; Janeth Leksell; Agneta Lindberg; Peter ..., PLoS ONE, 2018

by Carl Willers, Hanna Iderberg, Mette Axelsen, Tobias Dahlström, Bettina Julin, Janeth Leksell, Agneta Lindberg, Peter Lindgren, Karin Looström Muth, Ann-Marie Svensson, Mikael Lilja Background Socioeconomic status, origin or demographic attributes shall not determine the quality of healthcare ...

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26.06.2018 | Yunxiao Zhu; Zdravka Cankova; Marta Iwanaszko; Sheridan Lichtor; Milan Mrksich; Guillermo A. Ameer, Proceedings of the National Academy of Sciences current issue, 2018

The clinical management of nonhealing ulcers requires advanced materials that improve wound-closure rates without relying on the release of drugs or other growth factors that could potentially lead to concerns regarding systemic deleterious side effects. We report the synthesis, characterization, ...

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22.06.2018 | Aguirre-Plans, Joaquim ; Piñero, Janet ; Menche, Jörg ; Sanz, Ferran ; Furlong, Laura I.; Schmidt, Harald H. H. W. ..., Pharmaceuticals, 2018

Pharmaceuticals, Vol. 11, Pages 61: Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology Pharmaceuticals doi: 10.3390/ph11030061 Authors: Joaquim Aguirre-Plans Janet Piñero Jörg Menche Ferran Sanz Laura I. Furlong Harald H. H. W. ...

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22.06.2018 | Meredith Wadman, Science , 2018

The U.S. National Institutes of Health (NIH) in Bethesda, Maryland, last week killed a huge clinical trial probing the potential benefits of moderate drinking after an investigation found that senior officials at the agency's alcohol institute secretly and improperly wooed the alcoholic beverage ...

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15.06.2018 | Troy Morrison; Sara Jones; Ryan S. Causby; Kerry Thoirs, PLoS ONE, 2018

by Troy Morrison, Sara Jones, Ryan S. Causby, Kerry Thoirs Introduction Diabetes mellitus (DM) is associated with hyperglycaemia and advanced glycosylation end-products. In the foot, the consequences of chronic or uncontrolled diabetes are micro and macrovascular disease, neuropathy, reduced ...

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12.06.2018 | Yingduan Cheng; Quan Yuan; Laurent Vergnes; Xin Rong; Ji Youn Youn; Jiong Li; Yongxin Yu; Wei Liu; Hua Cai; Jiandie ..., Proceedings of the National Academy of Sciences current issue, 2018

Obesity has become a major epidemic around the globe, with fatal comorbidities such as type 2 diabetes, heart disease, and cancer that have led to alarming health concerns in modern medicine. Although excess adipose tissue is associated with negative metabolic outcomes, the physiological ...

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12.06.2018 | National Academy of Sciences, Proceedings of the National Academy of Sciences current issue, 2018

IMMUNOLOGY AND INFLAMMATION Correction for “Revealing the specificity of regulatory T cells in murine autoimmune diabetes,” by Allyson Spence, Whitney Purtha, Janice Tam, Shen Dong, Youmin Kim, Chia-Hsin Ju, Teague Sterling, Maki Nakayama, William H. Robinson, Jeffrey A. Bluestone, Mark S. ...

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06.06.2018 | Sunghwan Bae; Taesung Park, International Journal of Data Mining and Bioinformatics, 2018

Risk prediction of type 2 diabetes using common and rare variantsSunghwan Bae; Taesung ParkInternational Journal of Data Mining and Bioinformatics, Vol. 20, No. 1 (2018) pp. 77 - 90The recent development of next generation sequencing technology has led to the identification of several ...

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05.06.2018 | Rajesh Narasimamurthy; Sabrina R. Hunt; Yining Lu; Jean-Michel Fustin; Hitoshi Okamura; Carrie L. Partch; Daniel B. ..., Proceedings of the National Academy of Sciences current issue, 2018

Our innate circadian clocks control myriad aspects of behavior and physiology. Disruption of our clocks by shift work, jet lag, or inherited mutation leads to metabolic dysregulation and contributes to diseases, including diabetes and cancer. A central step in clock control is phosphorylation of ...

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03.06.2018 | Author(s): Mayur M. Patel, Bhoomika M. Patel, European Journal of Pharmaceutical Science, 2018

Publication date: 30 August 2018 Source:European Journal of Pharmaceutical Sciences, Volume 121 Author(s): Mayur M. Patel, Bhoomika M. Patel Background and purpose Diabetic patients are at greater risk for colon cancer. Histone deacetylases (HDACs) serve as common target for both. The ...

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