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709 Aktuelle Fachpublikationen zum Thema Diabetes Mellitus

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Can ultrasound measures of intrinsic foot muscles and plantar soft tissues predict future diabetes-related foot disease? A systematic review

15.06.2018 | Troy Morrison; Sara Jones; Ryan S. Causby; Kerry Thoirs, PLoS ONE, 2018

by Troy Morrison, Sara Jones, Ryan S. Causby, Kerry Thoirs Introduction Diabetes mellitus (DM) is associated with hyperglycaemia and advanced glycosylation end-products. In the foot, the consequences of chronic or uncontrolled diabetes are micro and macrovascular disease, neuropathy, reduced ...

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Repurposing of sodium valproate in colon cancer associated with diabetes mellitus: Role of HDAC inhibition

03.06.2018 | Author(s): Mayur M. Patel, Bhoomika M. Patel, European Journal of Pharmaceutical Science, 2018

Publication date: 30 August 2018 Source:European Journal of Pharmaceutical Sciences, Volume 121 Author(s): Mayur M. Patel, Bhoomika M. Patel Background and purpose Diabetic patients are at greater risk for colon cancer. Histone deacetylases (HDACs) serve as common target for both. The ...

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Accurate diagnosis of diabetes mellitus and new paradigms of classification

17.05.2018 | Sudesna Chatterjee; Melanie J. Davies, Nature Clinical Practice Endocrinology & Metabolism, 2018

Accurate diagnosis of diabetes mellitus and new paradigms of classification Accurate diagnosis of diabetes mellitus and new paradigms of classification, Published online: 17 May 2018; doi:10.1038/s41574-018-0025-1 A cluster analysis of five independent Swedish cohorts of people with diabetes ...

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The somatostatin-secreting pancreatic δ-cell in health and disease

17.05.2018 | Patrik Rorsman; Mark O. Huising, Nature Clinical Practice Endocrinology & Metabolism, 2018

The somatostatin-secreting δ-cells comprise ~5% of the cells of the pancreatic islets. The δ-cells have complex morphology and might interact with many more islet cells than suggested by their low numbers. δ-Cells contain ATP-sensitive potassium channels, which open at low levels of glucose but ...

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Targeting autophagy in obesity: from pathophysiology to management

23.04.2018 | Yingmei Zhang; James R. Sowers; Jun Ren, Nature Clinical Practice Endocrinology & Metabolism, 2018

Obesity poses a severe threat to human health, including the increased prevalence of hypertension, insulin resistance, diabetes mellitus, cancer, inflammation, sleep apnoea and other chronic diseases. Current therapies focus mainly on suppressing caloric intake, but the efficacy of this approach ...

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Interventions for lower extremity peripheral artery disease

20.04.2018 | Jade S. Hiramoto; Martin Teraa; Gert J. de Borst; Michael S. Conte, Nature Clinical Practice Cardiovascular Medicine, 2018

Peripheral artery disease (PAD) of the lower extremities is a common manifestation of atherosclerosis that is increasing in global prevalence and in the associated public health costs. Ageing of the general population, combined with the pandemics of diabetes mellitus, metabolic syndrome, and ...

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CKD in diabetes: diabetic kidney disease versus nondiabetic kidney disease

13.04.2018 | Hans-Joachim Anders; Tobias B. Huber; Berend Isermann; Mario Schiffer, Nature Clinical Practice Nephrology, 2018

The increasing global prevalence of type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD) has prompted research efforts to tackle the growing epidemic of diabetic kidney disease (DKD; also known as diabetic nephropathy). The limited success of much of this research might in part be due ...

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Does lower limb amputation concern all SGLT2 inhibitors?

06.04.2018 | André J. Scheen, Nature Clinical Practice Endocrinology & Metabolism, 2018

Does lower limb amputation concern all SGLT2 inhibitors? Does lower limb amputation concern all SGLT2 inhibitors?, Published online: 06 April 2018; doi:10.1038/s41574-018-0001-9 Sodium–glucose cotransporter 2 (SGLT2) inhibitors showed cardiorenal protection in patients with diabetes mellitus and ...

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Ultrafast glucose-responsive, high loading capacity erythrocyte to self-regulate the release of insulin

25.03.2018 | Author(s): Donglin Xia, Hong He, Ying Wang, Kaiyu Wang, Huaqin Zuo, Haiying Gu, Peipei Xu, Yong Hu, Acta Biomaterialia, 2018

Publication date: Available online 6 February 2018 Source:Acta Biomaterialia Author(s): Donglin Xia, Hong He, Ying Wang, Kaiyu Wang, Huaqin Zuo, Haiying Gu, Peipei Xu, Yong Hu Insulin (INS) delivery system that can mimic normal insulin secretion to maintain the blood glucose ...

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Prevalence of diabetic retinopathy and visual impairment in patients with diabetes mellitus in Zambia through the implementation of a mobile diabetic retinopathy screening project in the Copperbelt province: a cross-sectional study

05.03.2018 | Adam D. Lewis; Ruth E. Hogg; Manju Chandran; Lillian Musonda; Lorraine North; Usha Chakravarthy; Sobha Sivaprasad; G ..., Eye, 2018

A paucity of literature exists on prevalence of diabetic retinopathy (DR) in sub-Saharan Africa. We aim to estimate the prevalence of DR and visual impairment in Zambia’s Copperbelt province through a cross-sectional study. All patients with a diagnosis of diabetes mellitus attending a DR ...

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