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1.205 Aktuelle Fachpublikationen zum Thema Arthritis

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Safer anti-inflammatory therapy through dual COX-2/5-LOX inhibitors: A structure-based approach

24.06.2018 | Author(s): Jaismy Jacob P, S.L. Manju, K.R. Ethiraj, Geetha Elias, European Journal of Pharmaceutical Science, 2018

Publication date: 30 August 2018 Source:European Journal of Pharmaceutical Sciences, Volume 121 Author(s): Jaismy Jacob P, S.L. Manju, K.R. Ethiraj, Geetha Elias Inflammatory mediators of the arachidonic acid cascade from cyclooxygenase (COX) and lipoxygenase (LOX) pathways are ...

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Clinical manifestations of reported Lyme disease cases in Ontario, Canada: 2005–2014

01.06.2018 | Karen O. Johnson; Mark P. Nelder; Curtis Russell; Ye Li; Tina Badiani; Beate Sander; Douglas Sider; Samir N. Patel, PLoS ONE, 2018

by Karen O. Johnson, Mark P. Nelder, Curtis Russell, Ye Li, Tina Badiani, Beate Sander, Douglas Sider, Samir N. Patel Lyme disease (LD) is the most common vector-borne disease in Ontario, Canada. We describe the epidemiology and clinical manifestations of LD in Ontario and examine trends in the ...

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Diagnostic efficiency of Xpert MTB/RIF assay for osteoarticular tuberculosis in patients with inflammatory arthritis in China

01.06.2018 | Yuan Li; Wenyun Jia; Guohua Lei; Dan Zhao; Guirong Wang; Shibing Qin, PLoS ONE, 2018

by Yuan Li, Wenyun Jia, Guohua Lei, Dan Zhao, Guirong Wang, Shibing Qin Background Both osteoarticular tuberculosis (OA-TB) and inflammatory arthritis can lead to osteoarticular structural damage. These conditions exhibit similar symptoms, physical signs, and imaging features. Rapidly and ...

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Encapsulation of trans-aconitic acid in mucoadhesive microspheres prolongs the anti-inflammatory effect in LPS-induced acute arthritis

27.05.2018 | Author(s): Diego Pinto de Oliveira, Gabriela Guimarães Augusto, Nathália Vieira Batista, Vivian Louise S. de ..., European Journal of Pharmaceutical Science, 2018

Publication date: 1 July 2018 Source:European Journal of Pharmaceutical Sciences, Volume 119 Author(s): Diego Pinto de Oliveira, Gabriela Guimarães Augusto, Nathália Vieira Batista, Vivian Louise S. de Oliveira, Diêgo Santos Ferreira, Mateus Araújo Castro e Souza, Christian ...

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Polymer-lipid hybrid nanoparticles as enhanced indomethacin delivery systems

27.05.2018 | Author(s): Annalisa Dalmoro, Sabrina Bochicchio, Shamil F. Nasibullin, Paolo Bertoncin, Gaetano Lamberti, ..., European Journal of Pharmaceutical Science, 2018

Publication date: 30 August 2018 Source:European Journal of Pharmaceutical Sciences, Volume 121 Author(s): Annalisa Dalmoro, Sabrina Bochicchio, Shamil F. Nasibullin, Paolo Bertoncin, Gaetano Lamberti, Anna Angela Barba, Rouslan I. Moustafine Non-steroidal anti-inflammatory ...

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Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients

25.05.2018 | John C. Taylor; Tim Bongartz; Jonathan Massey; Borbala Mifsud; Athina Spiliopoulou; Ian C. Scott; Jianmei Wang; Mich ..., The Pharmacogenomics Journal, 2018

Methotrexate (MTX) monotherapy is a common first treatment for rheumatoid arthritis (RA), but many patients do not respond adequately. In order to identify genetic predictors of response, we have combined data from two consortia to carry out a genome-wide study of response to MTX in 1424 early RA ...

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Neurobiological similarities between RA and fibromyalgia

15.05.2018 | Fabiola Atzeni; Piercarlo Sarzi-Puttini, Nature Clinical Practice Rheumatology, 2018

Neurobiological similarities between RA and fibromyalgia Neurobiological similarities between RA and fibromyalgia, Published online: 15 May 2018; doi:10.1038/s41584-018-0011-y Pain management can be a difficult problem for patients with rheumatoid arthritis (RA), some of whom can experience pain ...

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Axial disease in psoriatic arthritis and ankylosing spondylitis: a critical comparison

11.05.2018 | Joy Feld; Vinod Chandran; Nigil Haroon; Robert Inman; Dafna Gladman, Nature Clinical Practice Rheumatology, 2018

Ankylosing spondylitis (AS) was first identified in the late 17th century. 250 years later, inflammatory spine disease was recognized to be one of the patterns of psoriatic arthritis (PsA). Isolated spondylitis is rare among patients with PsA, occurring in less than 5% of patients; however, many ...

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Rheumatoid arthritis: RA synovium harbours distinct fibroblast subsets

20.04.2018 | Sarah Onuora, Nature Clinical Practice Rheumatology, 2018

Rheumatoid arthritis: RA synovium harbours distinct fibroblast subsets Rheumatoid arthritis: RA synovium harbours distinct fibroblast subsets, Published online: 20 April 2018; doi:10.1038/nrrheum.2018.47 Rheumatoid arthritis: RA synovium harbours distinct fibroblast subsets

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Akkermansia muciniphila is permissive to arthritis in the K/BxN mouse model of arthritis

24.03.2018 | Matthew L Stoll; M Kathy Pierce; Jordan A Watkins; Mingce Zhang; Pamela F Weiss; Jennifer E Weiss; Charles O Elson; ..., Genes and Immunity, 2018

Studies have identified abnormalities in the microbiota of patients with arthritis. To evaluate the pathogenicity of human microbiota, we performed fecal microbial transplantation from children with spondyloarthritis and controls to germ-free KRN/B6xNOD mice. Ankle swelling was equivalent in ...

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