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A classification modeling approach for determining metabolite signatures in osteoarthritis

29.06.2018 | Jason S. Rockel; Weidong Zhang; Konstantin Shestopaloff; Sergei Likhodii; Guang Sun; Andrew Furey; Edward Randell; K ..., PLoS ONE, 2018

by Jason S. Rockel, Weidong Zhang, Konstantin Shestopaloff, Sergei Likhodii, Guang Sun, Andrew Furey, Edward Randell, Kala Sundararajan, Rajiv Gandhi, Guangju Zhai, Mohit Kapoor Multiple factors can help predict knee osteoarthritis (OA) patients from healthy individuals, including age, sex, and ...


Sociodemographic determinants and health outcome variation in individuals with type 1 diabetes mellitus: A register-based study

29.06.2018 | Carl Willers; Hanna Iderberg; Mette Axelsen; Tobias Dahlström; Bettina Julin; Janeth Leksell; Agneta Lindberg; Peter ..., PLoS ONE, 2018

by Carl Willers, Hanna Iderberg, Mette Axelsen, Tobias Dahlström, Bettina Julin, Janeth Leksell, Agneta Lindberg, Peter Lindgren, Karin Looström Muth, Ann-Marie Svensson, Mikael Lilja Background Socioeconomic status, origin or demographic attributes shall not determine the quality of healthcare ...


Introducing chaos behavior to kernel relevance vector machine (RVM) for four-class EEG classification

29.06.2018 | Enzeng Dong; Guangxu Zhu; Chao Chen; Jigang Tong; Yingjie Jiao; Shengzhi Du, PLoS ONE, 2018

by Enzeng Dong, Guangxu Zhu, Chao Chen, Jigang Tong, Yingjie Jiao, Shengzhi Du This paper addresses a chaos kernel function for the relevance vector machine (RVM) in EEG signal classification, which is an important component of Brain-Computer Interface (BCI). The novel kernel function has ...


Value of sample information in dynamic, structurally uncertain resource systems

29.06.2018 | Byron K. Williams; Fred A. Johnson, PLoS ONE, 2018

by Byron K. Williams, Fred A. Johnson Few if any natural resource systems are completely understood and fully observed. Instead, there almost always is uncertainty about the way a system works and its status at any given time, which can limit effective management. A natural approach to ...


Divide and conquer! Data-mining tools and sequential multivariate analysis to search for diagnostic morphological characters within a plant polyploid complex (Veronica subsect. Pentasepalae, Plantaginaceae)

29.06.2018 | Noemí López-González; Santiago Andrés-Sánchez; Blanca M. Rojas-Andrés; M. Montserrat Martínez-Ortega, PLoS ONE, 2018

by Noemí López-González, Santiago Andrés-Sánchez, Blanca M. Rojas-Andrés, M. Montserrat Martínez-Ortega This study exhaustively explores leaf features seeking diagnostic characters to aid the classification (assigning cases to groups, i.e. populations to taxa) in a polyploid plant-species ...


Therapeutic body wraps (TBW) for treatment of severe injurious behaviour in children with autism spectrum disorder (ASD): A 3-month randomized controlled feasibility study

29.06.2018 | Pierre Delion; Julien Labreuche; Dominique Deplanque; David Cohen; Alain Duhamel; Céline Lallié; Maud Ravary; Jean-L ..., PLoS ONE, 2018

by Pierre Delion, Julien Labreuche, Dominique Deplanque, David Cohen, Alain Duhamel, Céline Lallié, Maud Ravary, Jean-Louis Goeb, François Medjkane, Jean Xavier, on behalf of The Therapeutic Body Wrap Study group Introduction The use of therapeutic body wraps (TBW) has been reported in small ...


The analysis of genome composition and codon bias reveals distinctive patterns between avian and mammalian circoviruses which suggest a potential recombinant origin for Porcine circovirus 3

29.06.2018 | Giovanni Franzo; Joaquim Segales; Claudia Maria Tucciarone; Mattia Cecchinato; Michele Drigo, PLoS ONE, 2018

by Giovanni Franzo, Joaquim Segales, Claudia Maria Tucciarone, Mattia Cecchinato, Michele Drigo Members of the genus Circovirus are host-specific viruses, which are totally dependent on cell machinery for their replication. Consequently, certain mimicry of the host genome features is expected ...


A multiscale natural community and species-level vulnerability assessment of the Gulf Coast, USA

29.06.2018 | Joshua Steven Reece; Amanda Watson; Patricia Soupy Dalyander; Cynthia Kallio Edwards; Laura Geselbracht; Megan K. La ..., PLoS ONE, 2018

by Joshua Steven Reece, Amanda Watson, Patricia Soupy Dalyander, Cynthia Kallio Edwards, Laura Geselbracht, Megan K. LaPeyre, Blair E. Tirpak, John M. Tirpak, Mark Woodrey Vulnerability assessments combine quantitative and qualitative evaluations of the exposure, sensitivity, and adaptive ...


TV listening and hearing aids

29.06.2018 | Olaf Strelcyk; Gurjit Singh, PLoS ONE, 2018

by Olaf Strelcyk, Gurjit Singh TV listening plays a large role in the lives of hearing-impaired (HI) individuals. Yet, few studies have examined TV listening in this group. In this paper, we report the findings of an online survey on TV listening conducted among HI individuals with and without ...


Sweet taste receptor inhibitors: Potential treatment for equine insulin dysregulation

29.06.2018 | Melody Anne de Laat; Murad Hasan Kheder; Christopher Charles Pollitt; Martin Nicholas Sillence, PLoS ONE, 2018

by Melody Anne de Laat, Murad Hasan Kheder, Christopher Charles Pollitt, Martin Nicholas Sillence Hyperinsulinemia is a major risk factor for equine laminitis, a debilitating and painful foot condition. Sweet taste receptor (T1R2/3) inhibitors have been used to reduce the insulin and glucose ...


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