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3.415 Aktuelle Fachpublikationen in Journal of Proteome Research


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Neuropeptidomics of the Mosquito Aedes aegypti

05.04.2010 | Reinhard Predel; Susanne Neupert; Stephen F. Garczynski; Joe W. Crim; Mark R. Brown; William K. Russell; Jörg ..., Journal of Proteome Research, 2010

Neuropeptidomic data were collected on the mosquito Ae. aegypti, which is considered the most tractable mosquito species for physiological and endocrine studies. The data were solely obtained by direct mass spectrometric profiling, including tandem fragmentation, of selected tissues from single ...


Characterization of Cell Cycle Specific Protein Interaction Networks of the Yeast 26S Proteasome Complex by the QTAX Strategy

05.04.2010 | Robyn M. Kaake; Tijana Milenković; Nataša Pržulj; Peter Kaiser; Lan Huang, Journal of Proteome Research, 2010

Ubiquitin-proteasome dependent protein degradation plays a fundamental role in the regulation of the eukaryotic cell cycle. Cell cycle transitions between different phases are tightly regulated to prevent uncontrolled cell proliferation, which is characteristic of cancer cells. To understand cell ...


Analysis of Detergent-Insoluble and Whole Cell Lysate Fractions of Resting Neutrophils Using High-Resolution Mass Spectrometry

05.04.2010 | Gisele G. Tomazella; Idalete daSilva; Carolina H. Thomé; Lewis J. Greene; Christian J. Koehler; Bernd Thiede; ..., Journal of Proteome Research, 2010

Neutrophilic granulocytes play a major role in the initiation and resolution of the inflammatory response, and demonstrate significant transcriptional and translational activity. Although much was known about neutrophils prior to the introduction of proteomics, the use of MS-based methodologies ...


GlycoExtractor: A Web-Based Interface for High Throughput Processing of HPLC-Glycan Data

05.04.2010 | Natalia V. Artemenko; Matthew P. Campbell; Pauline M. Rudd; Natalia V. Artemenko; Matthew P. Campbell, Journal of Proteome Research, 2010

Recently, an automated high-throughput HPLC platform has been developed that can be used to fully sequence and quantify low concentrations of N-linked sugars released from glycoproteins, supported by an experimental database (GlycoBase) and analytical tools (autoGU). However, commercial packages ...


Identification of ΔNp63α Protein Interactions by Mass Spectrometry

05.04.2010 | Angela Amoresano; Antonella Di Costanzo; Gabriella Leo; Ferdinando Di Cunto; Girolama La Mantia; Luisa Guerrini; Vio ..., Journal of Proteome Research, 2010

p63, a transcription factor related to the p53 tumor suppressor, plays a key role in epidermal differentiation and limb development. The gene has two distinct promoters that allow the formation of proteins that either contain (TA) or lack (ΔN) a transactivation domain. ΔNp63α is the most widely ...


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