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2.543 Aktuelle Fachpublikationen in Journal of Biomedical Materials Research Part A

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S‐nitrosated poly(propylene sulfide) nanoparticles for enhanced nitric oxide delivery to lymphatic tissues

20.01.2018 | Alex Schudel, Lauren F. Sestito, Susan N. Thomas, Journal of Biomedical Materials Research Part A, 2018

Abstract Nitric oxide (NO) is a therapeutic implicated for the treatment of diseases affecting lymphatic tissues, which range from infectious and cardiovascular diseases to cancer. Existing technologies available for NO therapy, however, provide poor bioactivity within lymphatic tissues. In ...

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The in vitro release of cytokines and growth factors from fibrin membranes produced through horizontal centrifugation

18.01.2018 | E. S. Lourenço, C. F. A. B. Mourão, P. E. C. Leite, J. M. Granjeiro, M. D. Calasans‐Maia, G. G. Alves, Journal of Biomedical Materials Research Part A, 2018

Abstract Platelet‐rich fibrin (PRF) membranes are biomaterials widely used for therapeutic purposes, and canonically produced through the processing of peripheral blood with fixed‐angle rotor centrifuges. In this work, we evaluate the in vitro stability and release of cytokines and growth ...

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The in vitro release of cytokines and growth factors from fibrin membranes produced through horizontal centrifugation

18.01.2018 | E. S. Lourenço, C. F. A. B. Mourão, P. E. C. Leite, J. M. Granjeiro, M. D. Calasans‐Maia, G. G. Alves, Journal of Biomedical Materials Research Part A, 2018

Abstract Platelet‐rich fibrin (PRF) membranes are biomaterials widely used for therapeutic purposes, and canonically produced through the processing of peripheral blood with fixed‐angle rotor centrifuges. In this work, we evaluate the in vitro stability and release of cytokines and growth ...

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Recombinant collagen scaffolds as substrates for human neural stem/progenitor cells

17.01.2018 | Richard A. Que, Janahan Arulmoli, Nancy A. Da Silva, Lisa A. Flanagan, Szu‐Wen Wang, Journal of Biomedical Materials Research Part A, 2018

ABSTRACT Adhesion to the microenvironment profoundly affects stem cell functions, including proliferation and differentiation, and understanding the interaction of stem cells with the microenvironment is important for controlling their behavior. In this study, we investigated the effects of ...

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Development of a bi‐modal, in situ crosslinking method to achieve multi‐factor release from electrospun gelatin

17.01.2018 | Alysha P. Kishan, Taneidra Walker, Nick Sears, Thomas Wilems, Elizabeth M. Cosgriff‐Hernandez, Journal of Biomedical Materials Research Part A, 2018

Abstract To better mimic native tissue microenvironments, current efforts have moved beyond single growth factor delivery to more complex multiple growth factor delivery with distinct release profiles. Electrospun gelatin, a widely investigated drug delivery vehicle, requires post‐processing ...

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Hydrophobic and Hydrophilic Effects on Water Structuring and Adhesion in Denture Adhesives

13.01.2018 | Simrone K Gill, Nima Roohpour, Yiran An, Julien E Gautrot, Paul D Topham, Brian J Tighe, Journal of Biomedical Materials Research Part A, 2018

Abstract Denture adhesives are designed to be moisture‐sensitive through the inclusion of a blend of polymer salts with varying degrees of water‐sensitivity. This enables the adhesive to mix with saliva in vivo and activate its high tack, through the formation of a mucilaginous layer. We ...

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Hydrophobic and Hydrophilic Effects on Water Structuring and Adhesion in Denture Adhesives

13.01.2018 | Simrone K Gill, Nima Roohpour, Yiran An, Julien E Gautrot, Paul D Topham, Brian J Tighe, Journal of Biomedical Materials Research Part A, 2018

Abstract Denture adhesives are designed to be moisture‐sensitive through the inclusion of a blend of polymer salts with varying degrees of water‐sensitivity. This enables the adhesive to mix with saliva in vivo and activate its high tack, through the formation of a mucilaginous layer. We ...

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The Effect of Cell Density, Proximity, and Time on the Cytotoxicity of Magnesium and Galvanically Coupled Magnesium‐Titanium Particles in Vitro

11.01.2018 | Jua Kim, Jeremy L Gilbert, Journal of Biomedical Materials Research Part A, 2018

Abstract Magnesium (Mg) and galvanically‐coupled magnesium‐titanium (Mg‐Ti) particles in vitro have been reported previously to kill cells in a dosage‐dependent manner. Mg‐Ti particles kill cells more effectively than Mg alone, due to the galvanic effect of Mg and Ti. This study further ...

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Immunoisolating poly(ethylene glycol) based capsules support ovarian tissue survival to restore endocrine function

10.01.2018 | James R. Day, Anu David, Alexa L. Cichon, Tanay Kulkarni, Marilia Cascalho, Ariella Shikanov, Journal of Biomedical Materials Research Part A, 2018

Abstract A common irreversible adverse effect of life‐saving anticancer treatments is loss of gonadal endocrine function and fertility, calling for a need to focus on post‐treatment quality of life. Here, we investigated the use of poly(ethylene glycol)‐vinyl sulfone based capsules to support ...

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Phosphonate‐functionalized poly(β‐amino ester) macromers as potential biomaterials

10.01.2018 | Ece Akyol, Mirac Tatliyuz, Fatma Demir Duman, Melek Naz Guven, Havva Yagci Acar, Duygu Avci, Journal of Biomedical Materials Research Part A, 2018

Abstract Biodegradability, hemocompatibility, resistance to protein adsorption, and strong interactions with hydroxyapatite (HAP)‐based tissues such as dentin, enamel, and bone are important properties of phosphorus‐containing biomaterials. Here, novel phosphonate‐functionalized poly(β‐amino ...

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