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86.615 Aktuelle Fachpublikationen aus der Branche Medizin

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Innate immune sensor LGP2 is cleaved by the Leader protease of foot-and-mouth disease virus

29.06.2018 | Miguel Rodríguez Pulido; María Teresa Sánchez-Aparicio; Encarnación Martínez-Salas; Adolfo García-Sastre; Francisco ..., PLoS Pathogens, 2018

by Miguel Rodríguez Pulido, María Teresa Sánchez-Aparicio, Encarnación Martínez-Salas, Adolfo García-Sastre, Francisco Sobrino, Margarita Sáiz The RNA helicase LGP2 (Laboratory of Genetics and Physiology 2) is a non-signaling member of the retinoic acid-inducible gene-I (RIG-I)-like receptors ...

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Direct cell-to-cell transmission of respiratory viruses: The fast lanes

28.06.2018 | Nicolás Cifuentes-Muñoz; Rebecca Ellis Dutch; Roberto Cattaneo, PLoS Pathogens, 2018

by Nicolás Cifuentes-Muñoz, Rebecca Ellis Dutch, Roberto Cattaneo

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Methyl-CpG-binding (SmMBD2/3) and chromobox (SmCBX) proteins are required for neoblast proliferation and oviposition in the parasitic blood fluke Schistosoma mansoni

28.06.2018 | Kathrin K. Geyer; Sabrina E. Munshi; Helen L. Whiteland; Narcis Fernandez-Fuentes; Dylan W. Phillips; Karl F. Hoffmann, PLoS Pathogens, 2018

by Kathrin K. Geyer, Sabrina E. Munshi, Helen L. Whiteland, Narcis Fernandez-Fuentes, Dylan W. Phillips, Karl F. Hoffmann While schistosomiasis remains a significant health problem in low to middle income countries, it also represents a recently recognised threat to more economically-developed ...

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Biology must develop herd immunity against bad-actor molecules

28.06.2018 | Richard K. Plemper; Robert M. Cox, PLoS Pathogens, 2018

by Richard K. Plemper, Robert M. Cox

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Non-linear hierarchy of the quorum sensing signalling pathway in bloodstream form African trypanosomes

25.06.2018 | Lindsay McDonald; Mathieu Cayla; Alasdair Ivens; Binny Mony; Paula MacGregor; Eleanor Silvester; Kirsty McWilliam; K ..., PLoS Pathogens, 2018

by Lindsay McDonald, Mathieu Cayla, Alasdair Ivens, Binny Mony, Paula MacGregor, Eleanor Silvester, Kirsty McWilliam, Keith R. Matthews Trypanosoma brucei, the agents of African trypanosomiasis, undergo density-dependent differentiation in the mammalian bloodstream to prepare for transmission ...

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B cell clonal lineage alterations upon recombinant HIV-1 envelope immunization of rhesus macaques

22.06.2018 | Christina Yacoob; Miles Darnell Lange; Kristen Cohen; Kanan Lathia; Junli Feng; Jolene Glenn; Sara Carbonetti; Brian ..., PLoS Pathogens, 2018

by Christina Yacoob, Miles Darnell Lange, Kristen Cohen, Kanan Lathia, Junli Feng, Jolene Glenn, Sara Carbonetti, Brian Oliver, Vladimir Vigdorovich, David Noah Sather, Leonidas Stamatatos Broadly neutralizing HIV-1 antibodies (bNAbs) isolated from infected subjects display protective potential ...

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Prion replication environment defines the fate of prion strain adaptation

21.06.2018 | Elizaveta Katorcha; Nuria Gonzalez-Montalban; Natallia Makarava; Gabor G. Kovacs; Ilia V. Baskakov, PLoS Pathogens, 2018

by Elizaveta Katorcha, Nuria Gonzalez-Montalban, Natallia Makarava, Gabor G. Kovacs, Ilia V. Baskakov The main risk of emergence of prion diseases in humans is associated with a cross-species transmission of prions of zoonotic origin. Prion transmission between species is regulated by a species ...

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Flap endonuclease 1 is involved in cccDNA formation in the hepatitis B virus

21.06.2018 | Kouichi Kitamura; Lusheng Que; Miyuki Shimadu; Miki Koura; Yuuki Ishihara; Kousho Wakae; Takashi Nakamura; Koichi Wa ..., PLoS Pathogens, 2018

by Kouichi Kitamura, Lusheng Que, Miyuki Shimadu, Miki Koura, Yuuki Ishihara, Kousho Wakae, Takashi Nakamura, Koichi Watashi, Takaji Wakita, Masamichi Muramatsu Hepatitis B virus (HBV) is one of the major etiological pathogens for liver cirrhosis and hepatocellular carcinoma. Chronic HBV ...

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Origin of the poxviral membrane: A 50-year-old riddle

21.06.2018 | Bernard Moss, PLoS Pathogens, 2018

by Bernard Moss

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