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Staphylococcus aureus is the most common pathogen cultured from diabetic foot infection including diabetic foot osteomyelitis (DFOM). This French multicenter study determined the genetic content of S. aureus isolated from 157 consecutively cases admitted in 12 diabetic foot centres between 2008 and 2011. We describe for the first time the emergence of the CC398 methicillin‐susceptible S. aureus clone, the main clone in DFOM and its tropism for bone. This clone spreads to humans from animal source due to an intrinsic virulence. This adaptation of S. aureus isolates looks as a worrisome problem and should be carefully monitored.
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Abstract The single radial immunodiffusion assay has been the accepted method for determining the potency of inactivated influenza vaccines since 1978. The world‐wide adoption of this assay for vaccine standardisation was facilitated through collaborative studies that demonstrated a high ... mehr
Abstract Background Whether morbidity from the 1918‐19 influenza pandemic discriminated by socioeconomic status has remained a subject of debate for 100 years. In lack of data to study this issue recent literature have hypothesized that morbidity was “socially neutral”. Objectives ... mehr