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The New Generation: HPLC instrument with excellent precision and sensitivity as well as minimum sample carry-over A masterpiece of modern technology: HPLC System LaChrom Elite®

The new generation LaChrom Elite® system from VWR-Hitachi is a robust, versatile and well-designed HPLC instrument line with excellent precision and sensitivity as well as minimum sample carry-over. Designed for ease of use, all operational and maintenance parts are accessible from the front. Together with the comprehensive and FDA-compliant chromatography data system EZChrom Elite®, it offers a high degree of capability in data processing and chromatography system control.

Unique Detector Sensitivity
The new generation LaChrom Elite® system has extended its detector family by two new instruments, now offering unique sensitivity. The new L-2455 Diode Array Detector with an advanced reference wavelength function has extremely high sensitivity specifications, comparable to those of a very good UV detector. It can also be used as a multi-wavelength detector. The new L-2485 Fluorescence Detector demonstrates superb sensitivity, which allows analyses at the lowest trace levels.

From Micro to Standard HPLC
The LaChrom Elite® provides optimal performance within all flow rate ranges from 50 µl/min to 10 mL/min with 1, 2, 3, 4 and 4.6 mm i.d. columns as well as for high-speed chromatography using Chromolith® columns.

Fast Chromatography
The flow rate range 1-10 mL/min is ideal for fast chromatography using 3 or 4.6 mm i.d. Chromolith® columns. Using such columns, the speed of analysis can be increased by a factor of 3-10 compared with separations using conventional particulate columns, thus saving time and money in routine analysis. Their low back-pressure means less risk of leaks and a much longer lifetime of system components, increasing up-time and reliability while reducing the cost of analysis.

Superior temperature control for reliable results
In addition to the proven L-2300 Oven, the new generation LaChrom Elite® system offers the high-performance L-2350 Column Thermostat with excellent temperature homogeneity and an extended temperature range. It accommodates up to 8 columns. The increased temperature range now extending to 85 °C adds more versatility for high temperature applications. It can also be equipped with one or two valves for column switching, sample preparation by pre-column switching and other applications.

LC-MS
The LaChrom Elite® system can be easily combined with the esquire^TM and HCT^TM series ion trap or micrOTOF^TM series MS systems of Bruker Daltonics, thus offering exciting possibilities in mass detection, structural elucidation and substance identification in research and routine analysis.

Fast Automated Method Development
The LaChrom Elite® combined with the powerful ChromSword® Auto software performs completely automatic HPLC method development and optimization within hours. The target is optimum resolution with minimum analysis time so that even existing methods can be optimized and analysis time further reduced. In this way substantial time and cost savings can be achieved.

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