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| Article 1 to 10 out of 24 concerning Cold Spring Harbor Laboratory
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Scientists develop strategy to rapidly describe outbreak strains with next-generation DNA sequencing
(04/11/2008)
In the event of an outbreak or a bioterrorist attack, rapid identification of the genetic changes responsible for virulence or drug resistance is essential to mounting an effective response. Standard DNA sequencing and analysis of a pathogen genome ...
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Scientists reshape Y chromosome haplogroup tree gaining new insights into human ancestry
(04/02/2008)
The Y chromosome retains a remarkable record of human ancestry, since it is passed directly from father to son. In an article published in Genome Research, scientists have utilized recently described genetic variations on the part of the Y ...
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Researchers identify a worldwide-distributed clone of bacteria responsible for Legionnaire's disease
(02/06/2008)
A study published online in Genome Research describes new insights into Legionella pneumophila, the bacteria responsible for most cases of Legionnaires' disease. This report investigates the genetic background of L. pneumophila, provides clues to ...
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Link Uncovered Between Variation in Humans with Extreme Body Mass and Abnormal Splicing
(12/21/2007)
Researchers report new insights into how genetic variation may create phenotypic differences between individuals. This study, which investigates the influence of mutations associated with obesity on the mechanism of splicing, is published online in ...
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Domestic cat genome sequenced
(11/01/2007)
A report that appears in the scientific journal Genome Research details the first assembly, annotation, and comparative analysis of the domestic cat genome (Felis catus). The DNA of a 4-year-old Abyssinian cat named Cinnamon, whose well-documented ...
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Scientists show that mitochondrial DNA variants are directly linked to risk factors for type 2 diabetes
(08/13/2007)
Researchers report for the first time that genetic variants in mitochondria-energy-producing structures harboring DNA that are inherited only from the mother-are directly linked to metabolic markers for type 2 diabetes. The study, which highlights ...
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Genomics study provides insight into the evolution of unique human traits, including endurance running
(08/01/2007)
Researchers from the University of Colorado Health Sciences Center, along with colleagues from Stanford University, report the results of a large-scale, genome-wide study to investigate gene copy number differences among ten primate species, ...
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Scientists Discover New Role for MicroRNAs in Stopping Tumor Cell Growth
(06/22/2007)
Applied Biosystems Technology Helps to Reveal Cancer Fighting Function of Small RNAs
Scientists at Cold Spring Harbor Laboratory (CSHL), Howard Hughes Medical Institute (HHMI), and Applied Biosystems, an Applera Corporation business, have discovered that a family of small RNA molecules known as microRNAs (miRNAs) are components in a ...
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Scientists identify a candidate gene for osteoporosis
(03/29/2007)
Gene may underlie differences between African Americans and Caucasians
Researchers report the identification of a gene that may play a role in susceptibility to osteoporosis. The study, conducted by scientists at the Musculoskeletal Diseases Center of the Jerry L Pettis Memorial Veteran's Affairs Medical Center at Loma ...
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Scientists identify a gene that may suppress colorectal cancer
(03/22/2007)
Genome Research, a husband-and-wife research team from Thomas Jefferson University report the discovery of a gene that, when mutated, may suppress colorectal cancer. To conduct the study, the researchers used a strain of mice that develop polyps, or ...
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