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| Article 1 to 10 out of 64 concerning The Scripps Research Institute (TSRI)
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Light activated 'warhead' turns modest molecules into super protein killers
(16 Mar 2010)
Novel research tool from Scripps Florida could significantly expand search for new therapies
Using a novel light activation technique, Scripps Research Institute scientists have been able to turn molecules with only a modest ability to fight specific proteins into virtual protein destroyers. The new technique, which uses a "warhead" ...
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Schizophrenia gene network analysis identifies age-associated defects
(02 Mar 2010)
The underlying causes of the debilitating psychiatric disorder schizophrenia remain poorly understood. In a study published in Genome Research, scientists have performed a powerful gene network analysis that has revealed surprising new insights ...
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Scripps Research scientists find two compounds that lay the foundation for a new class of AIDS drug
(05 Feb 2010)
Novel therapies could improve potency of existing AIDS treatments, help to combat drug-resistant virus strains
A team of scientists at The Scripps Research Institute has identified two compounds that act on novel binding sites for an enzyme used by the human immunodeficiency virus (HIV), the virus that causes AIDS. The discovery lays the foundation for the ...
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Scientists Map Epigenome of Human Stem Cells During Development
(04 Feb 2010)
Billions of Data Points Provide Big Picture of "Human Epigenome” During Critical Developmental Window
Scientists at The Genome Institute of Singapore (GIS) and The Scripps Research Institute (TSRI) led an international effort to build a map that shows in detail how the human genome is modified during embryonic development. This detailed mapping is a ...
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Scripps Research scientists crack mystery of protein's dual function
(16 Dec 2009)
The work provides insight into potential therapeutic for cancer and eye diseases
Researchers at The Scripps Research Institute have solved a 10-year-old mystery of how a single protein from an ancient family of enzymes can have two completely distinct roles in the body. In addition to providing guidance for understanding other ...
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A major step in making better stem cells from adult tissue
(20 Oct 2009)
A team led by scientists from The Scripps Research Institute has developed a method that dramatically improves the efficiency of creating stem cells from human adult tissue, without the use of embryonic cells. The research makes great strides in ...
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Mechanism for potential Friedreich's ataxia drug uncovered
(29 Sep 2009)
Discovery takes researchers one step closer to human clinical trials and could improve understanding of other diseases
Using clever chemistry, a Scripps Research team has pinpointed the enzyme target of a drug group that stops the progression of the devastating disease Friedreich's ataxia in mice and may do the same for humans. The findings, developed in ...
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Rare genetic disease successfully reversed using stem cell transplantation
(21 Sep 2009)
Scripps Research scientists correct gene defect in mice that causes lethal symptoms in children
A recent study by Scripps Research Institute scientists offers good news for families of children afflicted with the rare genetic disorder, cystinosis. In research that holds out hope for one day developing a potential therapy to treat the fatal ...
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Two new antibodies found to cripple HIV
(07 Sep 2009)
HIV Findings reveal an Achilles heel on the virus for AIDS vaccine researchers to exploit
Researchers at and associated with the International AIDS Vaccine Initiative (IAVI), at The Scripps Research Institute, and at the biotechnology companies Theraclone Sciences and Monogram Biosciences have discovered two powerful new antibodies to ...
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Caltech chemists say antibody surrogates are just a 'click' away
(13 Jul 2009)
Chemists at the California Institute of Technology (Caltech) and the Scripps Research Institute have developed an innovative technique to create cheap but highly stable chemicals that have the potential to take the place of the antibodies used in ...
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