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| Article 1 to 10 out of 12 concerning Yale University
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Individual Differences Caused by Shuffled Chunks of DNA in the Human Genome
(10/01/2007)
A study by Yale researchers offers a new view of what causes the greatest genetic variability among individuals - suggesting that it is due less to single point mutations than to the presence of structural changes that cause extended segments of the ...
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Alnylam and Yale University Scientists Demonstrate Therapeutic Silencing of Disease Target
(11/08/2006)
Alnylam Pharmaceuticals, Inc. announced publication of data demonstrating that an RNAi therapeutic can silence angiopoietin 2 (Ang2), a key mediator in acute lung injury. In a paper published in Nature Medicine, scientists from Yale University and ...
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Elevated Testosterone Kills Nerve Cells
(10/02/2006)
A Yale School of Medicine study shows for the first time that a high level of testosterone, such as that caused by the use of steroids to increase muscle mass or for replacement therapy, can lead to a catastrophic loss of brain cells. Taking large ...
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Campus Vienna Biocenter: Nanostructures of the Infective Apparatus of Salmonella
(06/08/2006)
In Salmonella, structural changes to the molecular infection apparatus also signal an end to its further assembly. The mechanistic details of this sophisticated feedback system, which takes place at molecular level, have now been published. Better ...
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Link Between Esophageal Cancer and Soft Drinks Debunked by Researchers at Yale
(01/04/2006)
Carbonated soft drink consumption was previously suggested to be linked to the 350 percent increase of adenocarcinoma of the esophagus since the mid-1970s, but researchers at Yale School of Medicine report that the link is unfounded and that there ...
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A Powerful New Tool for Decoding Gene Functions in Mammals and Man
(08/16/2005)
A collaborative project between American and Chinese researchers developed a way to study the function of genes in mice and man by using a moveable genetic element from moths, according to a report in the journal Cell."We know how many genes are in ...
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Yale Scientists Identify Structure for RNA Quality Control
(06/06/2005)
A report by Yale scientists in the journal Cell sheds new light on how the protein Ro, a major autoantigen in patients with autoimmune disease, recognizes misfolded RNAs, creating a RNA quality control system for cells. The quality control process ...
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Plant Sacrifices Cells to Fight Invaders
(05/24/2005)
Gene ensures programmed cell suicide does not go unchecked
Researchers recently discovered a gene essential to one of the plant kingdom's key immune responses--programmed cell death (PCD). Plants use PCD to create a protective zone of dead cells around the infection site to prevent the invading pathogen ...
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Mood Elevating Hormone May Trigger Depression and Heart Problems
(03/08/2005)
Impaired function of a receptor that regulates release of a mood elevating hormone in the brain may be responsible for causing depression, anxiety and cardiovascular disorders, according to a Yale study in Pharmacogenetics and Genomics.The genetic ...
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Researchers Find Missing Genes of Ancient Organism
(02/17/2005)
Yale scientists report in the journal Nature (Nature 433: 537-541) that the "missing" genes for tRNA in an ancient parasite are made up by splicing together sequences in distant parts of the DNA genome.The research led by Professor Dieter Söll ...
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