Othera Files IND Application for OT-730 in Glaucoma (04 Aug 2008) Novel Treatment Promises Improved Safety over Existing Therapies the intraocular pressure in subjects with ocular hypertension or open-angle...) for OT-730, an oculoselective beta-blocker, as a potential treatment for glaucoma... for developing glaucoma. Beta-blockers as a class are among the most widely-prescribed drugs...