YAP is a mutation on the Y chromosome, which defines specific haplogroups. It exists in haplogroups, DE, D and E. A Y chromosome that has the YAP mutation is called YAP-positive (YAP+), and a Y chromosome that does not have the YAP mutation is called YAP-negative (YAP-).
The YAP mutation was caused when a strand of DNA called Alu, which copies itself, inserted a copy into the Y chromosome.
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