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Tetrahydrofolic acid
| Tetrahydrofolic acid |
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| Identifiers |
| CAS number |
29347-89-5 |
| PubChem |
1129 |
| MeSH |
5,6,7,8-tetrahydrofolic+acid |
| Properties |
| Molecular formula |
C19H23N7O6 |
| Molar mass |
445.43 g/mol |
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references |
Tetrahydrofolic acid is a folic acid derivative.
Metabolism
It is produced from dihydrofolic acid by dihydrofolate reductase. This reaction is inhibited by trimethoprim.
It is converted into 5,10-methylenetetrahydrofolate by serine hydroxymethyltransferase.
Functions
It is a coenzyme in many reactions, especially in the metabolism of amino acids and nucleic acids. It acts as a donor of a group with one carbon atom. It gets this carbon atom by sequestering formaldehyde produced in other processes. A shortage in THF can cause anemia.
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Tetrahydrofolic_acid". A list of authors is available in Wikipedia.
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