 |
|
|
|
 |
|
|
Tenase
The tenase complex is formed by the activated forms of the blood coagulation factors factor VIII and factor IX. It forms on a phospholipid surface in the presence of calcium and is responsible for the activation of factor X.
Tenase" is a contraction of "ten" and the suffix "-ase" used for enzymes
|
Pathology: hematology (primarily C81-C96/200-208, D45-D47, D50-D77/280-289) |
| WBCs |
hematological malignancy (lymphoma, leukemia, multiple myeloma), myeloproliferative disease, myelodysplastic syndrome
-cytosis (Agranulocytosis, Leukocytosis, Lymphocytosis, Monocytosis) • -penia (Lymphopenia, Neutropenia) |
RBCs/anemia/
hemoglobinopathy |
nutritional anemia: Iron deficiency anemia, Plummer-Vinson syndrome, Megaloblastic anemia (Pernicious anemia)
hereditary hemolytic anemia: G6PD Deficiency, Thalassemia, Sickle-cell disease/trait, Hereditary spherocytosis, Hereditary elliptocytosis, Hereditary stomatocytosis
acquired hemolytic anemia: Autoimmune (Warm), HUS, MAHA, PNH, PCH
aplastic anemia: Acquired PRCA, Diamond-Blackfan anemia, Fanconi anemia • Sideroblastic anemia • Hemochromatosis |
| Coagulation/platelets |
coagulopathy: DIC • Hemophilia (A/VII, B/IX, C/XI, XIII) • Von Willebrand disease
Purpura: Henoch-Schönlein, ITP (Evans syndrome), TTP
primary hypercoagulable state: Protein C deficiency - Protein S deficiency - Antithrombin III deficiency - Antiphospholipid syndrome - Factor V Leiden
other hemorrhagic conditions: Bernard-Soulier syndrome - Glanzmann's thrombasthenia - Grey platelet syndrome |
| Histiocytosis |
WHO-I Langerhans cell histiocytosis - non-Langerhans-cell histiocytosis/WHO-II (Juvenile xanthogranuloma, Hemophagocytic lymphohistiocytosis) - malignant histiocytic disorders/WHO-III (Acute monocytic leukemia, Malignant histiocytosis, Erdheim-Chester disease) |
| Other |
Asplenia/hyposplenism - Methemoglobinemia |
|
| |
|
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Tenase". A list of authors is available in Wikipedia.
|
|
|
|
|
|
Top