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Ruthenium red
Ruthenium red is a Ruthenium containing red staining dye.
The organic Ruthenium Red is polycationic cell biology reagent that tightly binds to tubulin dimers and Ryanodine receptor. It is a potent inhibitor of intracellular calcium release by Ryanodine receptors at nanomolar concentrations (km ~20 nM). [1]
The inorganic dye ammoniated ruthenium oxychloride used in histology to stain aldehyde fixed mucopolysaccharides, is sometimes also called Ruthenium red, and inhibits calcium transport through membrane channels.
References
- ^ TRIPATHY, LE XU ASHUTOSH, PASEK, DANIEL A., MEISSNER, GERHARD Potential for Pharmacology of Ryanadine Receptor/Calcium Release Channels Ann NY Acad Sci 1998 853: 130-148 [1]
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Ruthenium_red". A list of authors is available in Wikipedia.
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