Proflavine (pron. pro-fla¢vin), also called proflavin and diaminoacridine, is an acriflavine derivative, a disinfectant bacteriostatic against many gram-positivebacteria. It has been used in the form of the dihydrochloride and hemisulfate salts as a topical antiseptic, and was formerly used as a urinary antiseptic.
Proflavine is also known to have a mutagenic effect on DNA by intercalating between nucleic acidbase pairs. It differs from most other mutagenic components by causing basepair-deletions or basepair-insertions and not substitutions.
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