Life Science Encyclopedia

PROLI/NO (also "PROLINO" or "ProliNO") is the abbreviation of proline nitric oxide or proline NO. It is also referred to as a nitric oxide donor. It is an experimental drug, whose effects on vasospasms (or strokes) are being tested. It is a calcium inhibitor.

"prolino-" is also the prefix form of proline.

Sources

• Journal of Medicinal Chemistry: Localizing antithrombotic and vasodilatory activity with a novel, ultrafast nitric oxide donor
• British Journal of Pharmacology: Nitric oxide inhibits capacitative Ca2+ entry by suppression
• National Library of Medicine: Effects of nitric oxide on reactive oxygen species production and infarction size after brain reperfusion injury
• Nitric oxide and vasospasms