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Naringin
| Naringin |
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| Systematic name |
7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-
glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-
2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Other names |
Naringin
4',5,7-Trihydroxyflavanone-7-rhamnoglucoside
4',5,7-Trihydroxyflavanone-7-rutinoside |
| Chemical formula |
C27H32O14 |
| Molecular mass |
580.541 g/mol |
| Density |
? g/cm3 |
| Melting point |
166 °C |
| CAS number |
[10236-47-2] |
| SMILES |
OC(C=C3)=CC=[C@@]3[C@@H]2CC(C1=C(O)
C=C(O[C@H]4[C@H](O[C@]5([H])O[C@@H]
(C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)
[C@H](O)[C@@H](CO)O4)C=C1O2)=O |
| Disclaimer and references |
Naringin is the major flavonoid glycoside in grapefruit and gives grapefruit juice its bitter taste. It is metabolized to the flavanone naringenin in humans. Both naringenin and hesperetin, which are the aglycones of naringin and hesperidin, occur naturally in citrus fruits.
Activity
Narinigin exerts a variety of pharmacological effects such as antioxidant activity, blood lipid-lowering, anticarcinogenic activity, and inhibition of selected cytochrome P450 enzymes including CYP3A4 and CYP1A2, which may result in several drug interactions in-vitro. [1]
References
- ^ Grapefruit Juice and Medications
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Naringin". A list of authors is available in Wikipedia.
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