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Interleukin 3
Interleukin-3 (IL-3) is an interleukin, a type of biological signal (cytokine) that can improve the body's natural response to disease as part of the immune system.
IL-3 stimulates the proliferation of hematopoietic pluripotent progenitor cells. It is secreted by activated T cells to support growth and differentiation of T cells from the bone marrow in an immune response. The human IL-3 gene encodes a protein 152 amino acids long, and the naturally occurring IL-3 is glycosylated. The human IL-3 gene is located on chromosome 5, only 9 kilobases from the GM-CSF gene, and its function is quite similar to GM-CSF.
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Cytokines: interleukins |
| IL-1 superfamily |
IL-1 (IL-1Ra) - IL-18 - IL-33 |
| IL-6 like/gp130 utilizing |
IL-6 - IL-11 - IL-27 - IL-30 - IL-31 |
| IL-10 family |
IL-10 - IL-19 - IL-20 - IL-22 - IL-24 - IL-26 |
| Interferon type III |
IL-28 - IL-29 |
| Common γ-chain family |
IL-2/IL-15 - IL-3 - IL-4 - IL-7 - IL-9 - IL-13 - IL-21 |
| IL-12 family |
IL-12 - IL-23 - IL-27 - IL-35 |
| Other |
IL-5 - IL-8 - IL-14 - IL-16 - IL-17/IL-25 - IL-32 |
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Interleukin_3". A list of authors is available in Wikipedia.
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