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Hypertensive nephropathy

Hypertensive nephropathy
Classification & external resources
ICD-10 I12.
ICD-9 403

Hypertensive nephropathy (or "hypertensive nephrosclerosis", or "Hypertensive renal disease") is a medical condition referring to damage to the kidney due to chronic high blood pressure.

It should be distinguished from "renovascular hypertension" (I15.0), which is a form of secondary hypertension.

In the kidneys, as a result of benign arterial hypertension, hyaline (pink, amorphous, homogeneous material) accumulates in the wall of small arteries and arterioles, producing the thickening of their walls and the narrowing of the lumens — hyaline arteriolosclerosis. Consequent ischemia will produce tubular atrophy, interstitial fibrosis, glomerular alterations (smaller glomeruli with different degrees of hyalinization - from mild to sclerosis of glomeruli) and periglomerular fibrosis. In advanced stages, renal failure will occur. Functional nephrons have dilated tubules, often with hyaline casts in the lumens.

See also

  • Nephropathy


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Hypertensive_nephropathy". A list of authors is available in Wikipedia.
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