Fibrosis is the formation or development of excess fibrous connective tissue in an organ or tissue as a reparative or reactive process, as opposed to a formation of fibrous tissue as a normal constituent of an organ or tissue.

Fibrosis-related diseases and disorders:

• Cystic fibrosis of the pancreas and lungs
• Injection fibrosis, which can occur as a complication of intramuscular injections, especially in children
• Endomyocardial fibrosis, idiopathic myocardiopathy
• Cirrhosis can result from fibrosis of the liver
• Idiopathic pulmonary fibrosis of the lung
• Diffuse parenchymal lung disease
• Mediastinal fibrosis
• Myleofibrosis
• Post-Vasectomy Pain Syndrome
• Retroperitoneal fibrosis
• Progressive massive fibrosis, a complication of coal workers' pneumoconiosis
• Proliferative fibrosis, neoplastic fibrosis
• Tuberculosis (TB) can cause fibrosis of the lungs
• Sickle-cell anemia may cause enlargement and ultimately fibrosis of the spleen.
• Rheumatoid arthritis