Diphthamide: Encyclopedia with 57,945 entries from biotech, medicine & life sciences.

Life Science Encyclopedia

Diphthamide

Diphthamide

IUPAC name	2-Amino-3-[2-(3-carbamoyl-3-trimethylammonio-propyl)-3H-imidazol-4-yl]propanoate
Identifiers
CAS number	75645-22-6
PubChem	6438375
SMILES	C[N+](C)(C)C(CCC1=NC=C(N1)CC(C(=O)[O-])N)C(=O)N
Properties
Molecular formula	C₁₃H₂₃N₅O₃
Molar mass	297.35 g mol^-1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Diphthamide is a modified histidine amino acid found in eukaryotic elongation factor 2 (eEF-2). It is ADP-ribosylated by diphtheria toxin, which renders the elongation factor inactive.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Diphthamide". A list of authors is available in Wikipedia.