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Co-tenidone
Co-tenidone (BAN) is a non-proprietary name used to denote a combination of atenolol and chlortalidone. Co-tenidone is used in the treatment of hypertension. The use of β-blockers in hypertension was downgraded in June 2006 in the United Kingdom to fourth-line as they perform less well than other drugs, and that atenolol, the most frequently used β-blocker, at usual doses carries an unacceptable risk of provoking type 2 diabetes.[1]
Formulation
Two strengths of co-amilozide is currently available in the UK:
- 50 mg atenolol and 12.5 mg chlortalidone , BAN of Co-tenidone 50/12.5
- 100 mg atenolol and 25 mg chlortalidone , BAN of Co-tenidone 100/25
References
- British National Formulary 54 September 2007
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Antihypertensives (C02) and diuretics (C03) |
| Sympatholytic agents (including alpha) |
centrally acting/antiadrenergics (Clonidine, Guanfacine, Methyldopa, Moxonidine, Rescinnamine, Reserpine, Rilmenidine) • ganglion-blocking/nicotinic antagonist (Mecamylamine, Trimethaphan) • peripherally acting/antiadrenergics (Prazosin, Guanethidine, Indoramin, Doxazosin) |
| Vasodilators |
Diazoxide • Hydralazine • Minoxidil • Nitroprusside • Phentolamine |
| Other antihypertensives |
serotonin antagonist (Ketanserin) • endothelin receptor antagonist (Bosentan, Ambrisentan, Sitaxsentan) |
| Low ceiling diuretics |
Thiazide (Bendroflumethiazide, Chlorothiazide, Hydrochlorothiazide) • Chlortalidone • Indapamide • Quinethazone • Mersalyl • Metolazone • Theobromine • Cicletanine |
| High ceiling diuretics |
Loop diuretic (Bumetanide, Furosemide, Torasemide) |
| Potassium-sparing diuretics |
ESC blockers (Amiloride, Triamterene) • aldosterone antagonists (Spironolactone, Eplerenone, Potassium canrenoate, Canrenone) |
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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Co-tenidone". A list of authors is available in Wikipedia.
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