Ceftibuten
Ceftibuten
Systematic (IUPAC) name
(6R,7R)-7-([(Z)-2-(2-amino-1,3-thiazol-4-yl)-5-hydroxy-5-oxopent-2-enoyl]amino) -8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Identifiers
CAS number
97519-39-6
ATC code ?
PubChem 5282242
Chemical data
Formula
C 15 H 14 N 4 O 6 S 2
Mol. mass
410.427 g.mol-1
Pharmacokinetic data
Bioavailability ?
Metabolism ?
Half life
?
Excretion
?
Therapeutic considerations
Pregnancy cat.
?
Legal status
Routes ?
Ceftibuten is a third-generation cephalosporin antibiotic . It is an orally-administered agent, with 2 dosage forms, capsule or oral suspension. It is marketed by Shionogi USA under the trade name Cedax ®
Clinical use
Main article: Cephalosporin
Indications
Ceftibuten is used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
Formulations
Ceftibuten is available as capsules containing 400 mg, and a powder for oral suspension containing 90 mg per 5 ml.
See also
Antibacterials for systemic use: beta-lactam antibiotics - cephalosporins and related (J01D )
First generation
Cefacetrile, Cefadroxil , Cefalexin , Cefaloglycin, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole
Second generation
Cefaclor , Cefamandole, Cefmetazole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime
Third generation
Cefdinir , Cefditoren , Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime , Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime , Ceftibuten , Ceftizoxime, Ceftriaxone , Latamoxef
Fourth generation
Cefepime , Cefpirome, Cefquinome
Other beta-lactam antibacterials
Monobactams (Aztreonam ), Carbapenems (Meropenem , Ertapenem , Imipenem , Doripenem )
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