 |
|
|
|
 |
|
|
2-hydroxyphytanoyl-CoA lyase
|
2-hydroxyacyl-CoA lyase 1
|
| Identifiers |
| Symbol |
HACL1 |
| Alt. Symbols |
HPCL |
| Entrez |
26061 |
| HUGO |
17856 |
| OMIM |
604300 |
| RefSeq |
NM_012260 |
| UniProt |
Q9UJ83 |
| Other data |
| Locus |
Chr. 3 p24.3 |
2-Hydroxyphytanoyl-CoA lyase is a peroxisomal enzyme involved in the catabolism of phytanoic acid. It requires thiamine diphosphate (ThDP) as cofactor.[1]
It is classified under EC number 4.1.
References
- ^ Foulon V, Antonenkov V, Croes K et al. (1999). "Purification, molecular cloning, and expression of 2-hydroxyphytanoyl-CoA lyase, a peroxisomal thiamine pyrophosphate-dependent enzyme that catalyzes the carbon-carbon bond cleavage during alpha-oxidation of 3-methyl-branched fatty acids". Proc. Natl. Acad. Sci. U.S.A. 96 (18): 10039-44. PMID 10468558.
|
Carbon-carbon lyases (EC 4.1) |
| 4.1.1: Carboxy-lyases |
Pyruvate decarboxylase -Oxaloacetate decarboxylase - Acetoacetate decarboxylase - Malonyl-CoA decarboxylase - Glutamate decarboxylase - Ornithine decarboxylase - Lysine decarboxylase - Phosphoribosylaminoimidazole carboxylase - Histidine decarboxylase - Uridine monophosphate synthetase/Orotidine 5'-phosphate decarboxylase - Aromatic L-amino acid decarboxylase - Phosphoenolpyruvate carboxylase - Pyrophosphomevalonate decarboxylase - Uroporphyrinogen III decarboxylase - RuBisCO - Phosphoenolpyruvate carboxykinase - Adenosylmethionine decarboxylase |
| 4.1.2: Aldehyde-lyases |
Aldolase A/Aldolase B - 2-hydroxyphytanoyl-CoA lyase |
| 4.1.3: Oxo-acid-lyases |
3-hydroxy-3-methylglutaryl-CoA lyase |
|
| |
|
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "2-hydroxyphytanoyl-CoA_lyase". A list of authors is available in Wikipedia.
|
|
|
|
|
|
Top