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OncoMed Pharmaceuticals Inc 800 Chesapeake Drive 94063 Redwood City, CA USA Phone:  +1650-995-8200 Fax:  +1650-298-8600

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OncoMed Pharmaceuticals was founded in August 2004, by Drs. Michael F. Clarke and Max Wicha who led the discovery of cancer stem cells, in solid tumors. The cancer stem cell hypothesis suggests that tumors are composed of heterogeneous cell types and that cancer growth and metastasis are driven by a sub-population of cells within the tumor. The tumorigenic cells have been termed cancer stem cells because they exhibit certain properties similar to normal stem cells in adults that replenish tissues, such as the skin and the lining of the intestinal tract. The founders invented techniques to identify the subset of cells within a tumor that have stem cell like properties.

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