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19 Current white paper about the topic fluorescence

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Promotion of Aggregation as a Means of Assessing the Stability of Antibody Molecules

Thioflavin T aggregation assay to determine antibody stability using the FLUOstar Omega

03-11-2011

The efficiency of antibody molecules is dependent on their stability. We introduce an assay setup where stability of antibodies is measured. Shaking stress is initiated by the FLUOstar Omega microplate reader and aggregation propensity of antibody candidates is measured in 96-well format

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Miniaturised Platelet Aggregation Assays using the NOVOstar Microplate Reader

25-05-2011

Platelet aggregation is a “gold standard” assay of platelet function in the research and clinical laboratory settings which is conventionally measured with aggregometers requiring large volumes of platelet suspensions and only in low throughput format. With the NOVOstar microplate reader from BMG ...

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Increased productivity for downstream processing of biotherapeutics

16-11-2010

Polymer-based chromatographic resins featuring high mechanical and chemical stability and high protein binding capacities can help to increase the throughput and robustness of biopharmaceutical manufacturing processes. Advances in genetic engineering and cell culture technology have raised ...

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RealTime ready - Function Tested qPCR Assays Based on the Universal ProbeLibrary Technology

Gene expression profiling of the human genome on the LightCycler® 480 System has never been so easy.

14-12-2009

RealTime ready qPCR Assays redefine real-time qPCR because each assay is function-tested in PCR and qualified under strict criteria to assure superior performance. The RealTime ready Assays are based on the well-known Universal ProbeLibrary (UPL) technology and are available in a ready-to-use ...

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HelpCorner - Transfection

31-08-2009

Transfection is the delivery of DNA, RNA, proteins, and macromelecules into eukaryotic cells. The goals for transfection include the study of gene function and regulation as well as protein expression and function. It is also used for gene silencing and protein production. According to the ...

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Real-time and Dynamic Monitoring of Virus-mediated Cytopathogenicity

24-08-2009

To understand overall infectivity, virus progression and disease onset it is important to perform a detailed examination of cytopathic effects. Depending on the type of viruses and cells, different cytopathic effects might be observed dependent on the timepoint of infection (e.g., during the ...

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Analysis of Prostate Tumour Cell Invasion Using BD FluoroBlokTMand FLUOstar OPTIMA

Real-time analysis of tumour cell invasion with a FLUOstar OPTIMA enclosed in an AtmosBag

24-06-2009

The FLUOstar OPTIMA is used for reading the BD Biosciences FluoroBlok(TM) tumour cell invasion system. In this application note we show that the results are comparable to the traditional invasion assays. The introduced method is fast, saving time and labour. The FLUOstar OPTIMA is able to take ...

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qPCR Identification of Genes Involved in Apoptosis and Cell Cycle Regulation

10-06-2009

Systematic high-throughput functional genomic screens with the targeted silencing of genes by the introduction of small interfering RNA (siRNA) have emerged as an extremely powerful tool for analysis of biological functions. Such screens commonly result in a huge amount of "hits", genes that ...

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New Standard in Electrophysiology and Deep Tissue Imaging

The Confocal Fixed Stage System Leica DM6000 CFS

08-04-2009

The function of nerve and muscle cells relies on ionic currents flowing through ion channels. These ion channels play a major role in cell physiology. One way to investigate ion channels is to use patch clamping. This method allows investigation of ion channels in detail and recording of the ...

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