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118 Current white paper of Roche Diagnostics

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Continuous non-invasive real-time cell monitoring in 384-well plates

xCELLigence RTCA HT Instrument for high throughput cell analytics

14-02-2012

#img11505# Roche’s xCELLigence System RTCA HT Instrument performs real-time impedance-based label-free measurement of cell behavior for high throughput applications. It´s technology is compatible with workflows carrying out automated screening using the 384-well culture plate format. One to ...

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Non-Invasive Real-Time Cell Analytics for Drug Discovery

xCELLigence Cardio Instrument for Cardiac Safety Assessment

14-02-2012

Roche’s xCELLigence Cardio Instrument is a medium-throughput cell analyzer using impedance recording to monitor cardiac beating and cellular events in real time. The instrument features high resolution detection rate and frequency measurement technology driven by dedicated software. Unlike ...

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Cannabis genome sequenced with 454 GS FLX+ System

Long high-resolution reads for medical genomics

07-02-2012

#img11503# Medicinal Genomics, a private company headquartered in Marblehead, Massachuetts, USA and the Netherlands, sequenced the entire genomes of Cannabis sativa and Cannabis indica, two strains of the therapeutic plant. These largest known Cannabis genome assemblies comprise over 131 ...

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RealTime ready qPCR Assay Design and Configuration Portal Content

01-06-2011

Abstract The RealTime ready Configurator is a web-based configuration and ordering portal for function tested, custom RT-qPCR assays based on Universal ProbeLibrary (UPL) technology. It contains consolidated gene annotation information derived from three key public gene annotation resources ...

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RealTime ready RT-qPCR Assay Development and Qualification

01-06-2011

Abstract On the RealTime ready Configurator [1], we offer function tested human, mouse, and rat qPCR assays for gene expression quantification based on the unique Universal ProbeLibrary technology (UPL) [2]. The Universal ProbeLibrary is a set of short hydrolysis probes (8–9-mers) containing ...

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Nobel Prize for Solving the End-Replication Problem

27-01-2010

The Nobel Assembly awarded this year’s Nobel Prize in Medicine to Elizabeth H. Blackburn, Jack W. Szostak, and Carol W. Greider for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase. With their ingenious genetic research and meticulous biochemical studies, ...

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HelpCorner - xCELLigence System

25-01-2010

General FAQ: How can I save time when using the xCELLigence System? HelpCorner: Automated monitoring and data collection contribute to significant time savings when using the xCELLigence System, with only a few minutes of extra setup time (Figure 1). For example, in a 96-well plate, 32 ...

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High-Throughput Cardiac Gene Expression Analysis Using the Universal ProbeLibrary and the Novel LightCycler® 1536 Real-Time PCR System

25-01-2010

Introduction Although congenital heart malformations are the most common birth defects in humans, the underlying patho­mechanisms remain widely unknown. Through linkage analyzes and candidate-gene approaches, several gene mutations causing congenital heart defects (e.g., CITED2, GATA4, ...

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MagNA Pure 96 Cellular RNA Kits: RNA Isolation on the Fast Lane

18-01-2010

Introduction Advancements in high-throughput gene expression analysis have set a new demand for automated isolation of cellular RNA from high sample numbers in parallel. The availability of the innovative MagNA Pure 96 System together with dedicated kits, protocols, and consumables sets a ...

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The New MagNA Pure 96 DNA and Viral NA Kits: Maximal Speed Combined with High Recovery

18-01-2010

Introduction The MagNA Pure 96 System is a brand-new system recently introduced to the market: it is a fully automated, ultra-fast system for high-throughput isolation of high- quality nucleic acids from various sample types that can handle sample volumes of up to 1 ml. The main features ...

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