Virology

Companies Virology

News Virology

• Study uncovers how herpesvirus spreads

  Herpesviruses are thrifty reproducers - they only send off their most infectious progeny to invade new cells. Two Cornell virologists recently have discovered how these viruses determine which progeny to release.The College of Veterinary Medicine researchers report in Proceedings of the National Aca more

• Deciphering how CD4 T cells die during HIV infection

  Scientists at Gladstone Institute of Virology and Immunology have solved a long-standing mystery about HIV infection–namely how HIV promotes the death of CD4 T cells. It is the loss of this critical subset of immune cells that leads to the development of AIDS. Most immune cells that die during HIV i more

• Katholieke Universiteit Leuven enters into license agreement with Pfizer for the development of new anti-HIV drugs

  Katholieke Universiteit Leuven (K.U.Leuven, Belgium) announced that on July 29th, 2010 they entered into a license agreement with Pfizer. The license agreement grants Pfizer exclusive and sublicenseable worldwide rights to further develop and commercialise K.U.Leuven’s compounds with a new mechanism more

White papers Virology

• Real-Time Multiplex PCR of five Different DNA Targets Using the LightCycler® 480 System
  

  One of the most interesting aspects of real-time PCR based on detection of fluorophoric-labeled oligonucleo­tides, such as Hydrolysis probes, and Molecular Beacons, is the possibility of being able to detect conveniently multiple targets in the same PCR reaction (multiplex PCR). Ideally, a real-time multiplex PCR should be able to detect, differentiate, and provide a quantitative result for many different targets without a single target influencing the detection of one of the others (cross-talk) and without loss of sensitivity. It is evident that due to the limited number of fluorophoric labels available and the significant overlap in their emission spectra, quantification of multiplex reaction products is difficult and often not possible for more than two targets. more

• Fugene® HD Transfection Reagent: Superior Performance for Challenging Expression Studies
  

  The ability to efficiently introduce foreign molecules into cells constitutes an important tool in any laboratory and facilitates studies of gene regulation and protein function. A plethora of transfection methods have been developed for transfer of DNA into mammalian and animal cells. Those methods either utilize the physicochemical properties of the vector-carrier of the DNA or use mammalian viruses. In the first group of methods, some classic techniques are well-known, such as: calcium phosphate, DEAE-dextran, electroporation liposome-mediated delivery, direct microinjection/biolistic particle delivery, and non-liposomal multi-component reagents. Viral vector systems use both DNA (Adeno-) and RNA (Retro-, Lenti-) viruses. more

• Efficient Transfection of VeroE6 Cells with DNA and RNA for Luciferase Reporter Assays Using FuGENE® HD Transfection Reagent
  

  The interferon (IFN) system of mammalian cells is the first line of defense against viral infections. Following infection, danger signals such as double-stranded RNA or single-stranded RNA with an unmodified 5´ triphosphate end (e.g., VSV-RNA) are recognized by membrane-bound Toll-like receptors and/or cytoplasmic receptors (MDA5, RIG-I). This initiates a signal cascade which leads to the production of type I interferons. By autocrine and paracrine stimulation via the IFN-a/b receptor the expression of antiviral proteins is induced in the infected cell as well as in the surrounding cells. more

Publications Virology

• [Perspective] Virology: Our Viral Inheritance

  Viruses incorporated into vertebrate genomes may reemerge after long periods of dormancy to play a range of biological roles in their host. more

• Microarray resources for genetic and genomic studies in chicken: A review

  Abstract Advent of microarray technologies revolutionized the nature and scope of genetic and genomic research in human and other species by allowing massively parallel analysis of thousands of genomic sites. They have been used for diverse purposes such as for transcriptome analysis, CNV detect more

• Virus Neutralisation: New Insights from Kinetic Neutralisation Curves

  by Carsten Magnus Antibodies binding to the surface of virions can lead to virus neutralisation. Different theories have been proposed to determine the number of antibodies that must bind to a virion for neutralisation. Early models are based on chemical binding kinetics. Applying these m more

Market studies Virology

• Infectious Immunology Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017

  Introduction GlobalData’s new report, “Infectious Immunology Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017” provides key market data on the Infectious Immunology market in the BRICS countries. The report provides value ($m) data for each segment and sub-segment within more

• World Influenza Vaccines Market 2011-2021

  Are you looking for influenza vaccine market data - answers to benefit your work? Our new report shows you revenue prospects for the manufacture and sale of influenza vaccines from 2009 to 2021. There, you will see commercial opportunities for influenza vaccines - original research, data and opini more

• Roche Diagnostics Limited - Product Pipeline Analysis

  Roche Diagnostics Limited - Product Pipeline Analysis Summary Roche Diagnostics Limited (Roche Diagnostics), a division of F. Hoffmann-La Roche Ltd. is engaged in the research, development, manufacture and marketing of diagnostic products for the healthcare markets. It also manufactures research r more

Websites Virology