Validation

Companies Validation

CANDOR Bioscience GmbH, Germany

CANDOR - The ELISA Experts Stabilizers and Optimizers for Immunoassays CANDOR Bioscience GmbH offers buffer and solutions for optimising and stabilising immunoassays. For reliable results. • LowCross-Buffer® - Optimizer developed to minimise interference such as non-specific binding, cross react more

Products Validation

Safety beyond the visible: Merck Millipore BioMonitoring

BioMonitoring is about innovative testing solutions, regulatory expertise, comprehensive service, and trust more

Regularly testing ensures correct UV/Vis measurement results

Spectrophotometers are measuring devices that have to provide continuously reliable and correct measuring results. To ensure this one should qualify more

Software Validation

ProControl®-AtOnce - Applied Statistics for Laboratories and Industries

Tests, Validation, Calibration, Spiking, Collaboratory Studies, Trends, Poolability, Stability, Forecast, Uncertainty, Dissolution, Specifications more

Videos Validation

ProControl®-AtOnce - Applied Statistics for Laboratories and Industries

ProControl provides statistical characteristics of measured data quick and easy. Theobjectives are validation, calibration, collaboratory studies, trend analysis and forecast including uncertainty, control charts and capability studies - just to mention some features.ProControl is based on standard more

News Validation

• Affimed enrolls first patients in Phase I Hodgkin's Lymphoma Study

  Affimed Therapeutics AG announced that the first patients with Hodgkin's Lymphoma have been treated with the AFM13 TandAb® antibody in a Phase I clinical study. The Phase I repeat dose escalation study will enroll approximately 40 Hodgkin's Lymphoma patients across two centers in Europe and the US. more

• Singapore Launches Infrastructure for Metrology in Chemistry (MiC)

  The National Metrology Centre (NMC) of the Agency for Science, Technology and Research (A*STAR) and the Health Sciences Authority (HSA) have jointly set up a national Metrology in Chemistry (MiC) infrastructure. Senior Minister of State for Trade and Industry and Education, Mr S. Iswaran announced t more

• Dako and Quintiles form alliance to speed development of personalized medicine

  Dako and Quintiles announced a strategic alliance to advance personalized medicine by collaborating on the co-development of targeted therapies and companion diagnostics. Under the non-exclusive alliance, Dako and Quintiles will offer integrated drug-diagnostic development services and companion dia more

White papers Validation

• Acquired Copy Number Alterations in Adult Acute Myeloid Leukemia Genomes
  

  To complement cytogenetic studies and to identify genes altered in AML genomes, Walter and co-workers performed a genome-wide copy number analysis with paired normal and tumor DNA obtained from 86 adult subjects with de novo AML using 1.85 million feature SNP arrays. A total of 201 somatic CNAs were found in the 86 AML genomes (mean, 2.34 CNAs per genome), with FAB-System M6 and M7 genomes containing the most changes (10-29 CNAs per genome). According to the authors' conclusions, the use of an unbiased high-resolution genomic screen identified many genes not previously implicated in AML that may be relevant for pathogenesis, along with many known oncogenes and tumor suppressor genes. Despite the ability of next-generation sequencing platforms to accurately identify amplifications, deletions, and translocations, a multiplatform approach (traditional cytogenetics, FISH, SNP array, array CGH, and targeted gene resequencing) will continue to be the most practical approach to studying AML genomes at most institut more

• qPCR Validation of Candidates for Modulators of the MAPkinase Signaling Pathway
  

  With the completion of the human genome sequence, the detailed understanding of gene functions by analyzing the structure, biological activities, and dynamics of the encoded proteins has become the next challenge. The technology of RNA interference (RNAi), which allows the silencing of genes by introduction of small interfering RNA (siRNA), is recognized as an extremely powerful tool for systematic high-throughput functional genomic screening. more

• Simulated Moving Bed Chromatography: from chiral molecules to biocompounds
  

  The Simulated moving bed (SMB) technology was developed in the '60s and used for large-scale separations of hydrocarbons in the oil industry. The SMB concept has been extended towards new fields of application since then, first in the large-scale food industry, e.g. separation of sugars, and lately in the separation of fine chemicals, particularly chiral molecules where it is now an established technique more

Publications Validation

• MicroRNA-1291-mediated silencing of IRE1{alpha} enhances Glypican-3 expression [ARTICLES]

  MicroRNAs (miRNA) are generally described as negative regulators of gene expression. However, some evidence suggests that they may also play positive roles. As such, we reported that miR-1291 leads to a GPC3 mRNA expression increase in hepatoma cells through a 3' untranslated region (UTR)-dependent more

• Deciphering the 8q24.21 association for glioma

  We have previously identified tagSNPs at 8q24.21 influencing glioma risk. We have sought to fine-map the location of the functional basis of this association using data from four genome-wide association studies, comprising a total of 4147 glioma cases and 7435 controls. To improve marker density ac more

• A genome-wide meta-analysis identifies two novel loci associated with high myopia in the Han Chinese population

  High myopia, highly prevalent in the Chinese population, is a leading cause of visual impairment worldwide. Genetic factors play a critical role in the development of this visual disorder. Genome-wide association studies in recent years have revealed several chromosomal regions that contribute to i more

Market studies Validation

• Miraculins Inc. - Strategic SWOT Analysis Review

  Miraculins Inc (Miraculins) is a research and development company engaged in the discovery and validation of cancer biomarkers, which enable the development of diagnostic tools and therapeutic products. The company focuses on biomarker discovery using its proprietary B.E.S.T Platform for the screeni more

• Arvind Remedies Ltd (531823) - Financial and Strategic SWOT Analysis Review

  Arvind Remedies Ltd (Arvind Remedies) is a publicly held pharmaceutical company. It is engaged in manufacturing and marketing of allopathic and ayurvedic pharmaceutical products. The company's main focus areas are development of drug delivery systems, new formulations and process development of vari more

• GE Measurement & Control Solutions - Strategic SWOT Analysis Review

  GE Measurement & Control Solutions is a technology instruments company, engaged in the design, manufacture and sale of the advanced sensing and measurement solutions. The company develops products such as sensing elements, devices, instruments, and systems which are utilized in monitor, protect, con more

Websites Validation