Key discoveries offer significant hope of reversing antibiotic resistance
Resistance to antibiotics is becoming increasingly prevalent and threatens to undermine healthcare systems across the globe. Antibiotics including penicillins, cephalosporins and carbapenems are known as β-lactams and are the most commonly prescribed worldwide.
In the first paper, Universit ... more
New research shows that proteins are 'virtually' knotted
Many of the processes essential to life involve proteins - long molecules which 'fold' into three-dimensional shapes allowing them to perform their biological role.
Consisting of strings of amino acids, a folded protein molecule resembles a coiled, tangled piece of wire, which, as everyday ... more
How bacteria resists 'last-resort' antibiotic
An international research team, led by the University of Bristol, has provided the first clues to understand how the mcr-1 gene protects bacteria from colistin - a 'last resort' antibiotic used to treat life-threatening bacterial infections that do not respond to other treatment options.
La ... more