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News UIC

• Newly demonstrated capabilities of low-powered nanotweezers may benefit cellular-level studies
  

  Using ultra-low input power densities, researchers at the University of Illinois at Urbana-Champaign have demonstrated for the first time how low-power "optical nanotweezers" can be used to trap, manipulate, and probe nanoparticles, including fragile biological samples. "We already know that plasmon more

• New tagging technique enhances view of living cells

  Scientists hoping to understand how cells work may get a boost from a new technique to tag and image proteins within living mammalian cells. The new technique, developed by a research team led by University of Illinois at Chicago assistant professor of chemistry Lawrence Miller, provides the cleare more

• Antibiotics might team up to fight deadly staph infections

  Researchers at the University of Illinois at Chicago and Israel's Weizman Institute of Science have found that two antibiotics working together might be more effective in fighting pathogenic bacteria than either drug on its own. Individually, lankacidin and lankamycin, two antibiotics produced nat more

Publications UIC

• A structure-based protocol for learning the family-specific mechanisms of membrane-binding domains

  Motivation: Peripheral membrane-targeting domain (MTD) families, such as C1-, C2- and PH domains, play a key role in signal transduction and membrane trafficking by dynamically translocating their parent proteins to specific plasma membranes when changes in lipid composition occur. It is, however, more

• Seasons but not ethnicity influence urinary iodine concentrations in Belgian adults

  Background Mild iodine deficiency (MID) is endemic in Belgium. Previous surveys, which assessed iodine nutrition in Belgium, focused on children. The iodine status of adults and the influence of ethnicity or seasonality on urinary iodine concentrations (UIC) have not been investigated. Since the nut more

• Cylindrocyclophanes with Proteasome Inhibitory Activity from the Cyanobacterium Nostoc sp.

  Material collected from a parkway in the city of Chicago afforded the isolation of a Nostoc species (UIC 10022A). The extract of this strain displayed significant inhibition of the 20S proteasome as well as antiproliferative activity against HT29, MCF7, NCI-H460, and SF268 cancer cell lines. A stand more

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