Tosoh Bioscience

Products Tosoh Bioscience

TSKgel Protein C4-300 – Speed and resolution for proteins analysis

Tosoh Bioscience is introducing a new reversed phase HPLC column for the separation of intact proteins. TSKgel Protein C4-300 consists of a polymerically bonded butyl more

Fast and efficient characterization of water soluble polymers

TSKgel SuperMultiporePW SEC columns provide near linear calibration curves for the analysis of size distributions of polymers, such as PVP or dextran more

Increase throughput and robustness of your antibody purification

TOYOPEARL AF-rProtein A affinity resin is well-suited for capturing of antibodies out of high titre feedstocks more

Catalogues Tosoh Bioscience

Everything you need to know about gel filtration on TSKgel HPLC columns

Tosoh Bioscience, a leading supplier of SEC technology, presents a new brochure featuring the use of TSKgel columns for SEC with aqueous mobile phases more

Videos Tosoh Bioscience

Increase throughput and robustness of your antibody purification

TOYOPEARL AF-rProtein A-650F combines a high binding capacity at short residence time and fast mass transfer kinetics with alkaline stability. Protein A based affinity chromatography is the industry standard for the capture of monoclonal antibodies (MAbs) in downstream processing. Rising fermentatio more

News Tosoh Bioscience

• Tosoh Bioscience celebrates its 20th Anniversary
  

  20 years ago, on July 20, 1989, TosoHaas opened the doors to the Biopharmaceutical industry. Starting out with a team of five employees, TosoHaas, over time, developed into a profitable business with constant growth. In the start TosoHaas focused on promoting the nowadays well known TSK-GEL SW and more

• Tosoh, Gen-Probe Sign Cross-Licensing Agreement For Nucleic Acid Testing Technologies

  Tokyo, Japan and San Diego, U.S. - Tosoh Corporation and Gen-Probe announced today that the companies have cross-licensed intellectual property covering certain nucleic acid testing (NAT) technologies. The licenses, which are effective January 1, 2004, cover products in clinical diagnostics and othe more

White papers Tosoh Bioscience

• Increased productivity for downstream processing of biotherapeutics
  

  Polymer-based chromatographic resins featuring high mechanical and chemical stability and high protein binding capacities can help to increase the throughput and robustness of biopharmaceutical manufacturing processes. Advances in genetic engineering and cell culture technology have raised upstream productivity in the production of recombinant proteins. Increased titres of up to 10 g/l stress the need for highly efficient and robust downstream processes (DSP). Most industrial bioprocess development groups apply generic DSP platforms that are designed to purify various candidates of the same class of proteins applying the same process design. Besides various filtration and virus inactivation steps, they usually involve two or three chromatographic unit operations with orthogonal separation modes. The use of high capacity chromatographic resins can help to overcome the DSP bottleneck by increasing process throughput and robustness more

• Characterizing Biotherapeutics with HPLC
  

  As demonstrated here, there are a broad range of HPLC applications used in development, production, validation and release of protein therapeutics for human use. Some of the applications mentioned above are mandatory when submitting a new biopharmaceutical to approval at the regulatory agencies. The introduction of the first so-called biosimilars in Europe further increased the demand for highly efficient analysis methods. The continuous development of new stationary phases for the common modes of biochromatography, such as size exclusion, ion exchange and hydrophilic interaction chromatography support biochemists in increasing lab productivity and establishing high-throughput HPLC analysis not only for small molecules but also for large biopolymers more

Websites Tosoh Bioscience