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• Pinhead-size worms + robot = new antibiotics

  In an advance that could help ease the antibiotic drought, scientists in Massachusetts are describing successful use of a test that enlists pinhead-sized worms in efforts to discover badly needed new antibiotics. Frederick Ausubel and colleagues note in the new study that existing methods for iden more

• First Published Study of New HPV Test for Developing Countries Shows High Accuracy in Predicting Cervical Disease

  A new HPV (human papillomavirus) test developed by QIAGEN specifically for use in regions of the world with scarce resources is "substantially" more accurate in identifying women with cervical disease than the current methods (Pap testing and visual inspection) in these countries. The first publishe more

• Sperm stem cells closer to being like embryonic stem cells

  New experiments that prevented rat sperm stem cells from changing permanently into sperm have brought researchers one step closer to coaxing such cells to behave like embryonic stem cells, capable of growing into many other types of cells in the body. Researchers at the Cecil H. and Ida Green Cente more

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• Eternal shelf-life for ELISA?
  

  Reliable long-term stabilization of immunoassay components is beneficial in many applications. Stabilization and storage of components are important for effective workflows not only for performing large numbers of ELISA but also for medium and small numbers of ELISA. This article deals with the state of the art - particularly with regard to food, veterinary or clinical diagnostics. Clinical immuno diagnostics require adequate stabilization of assay components according to EU guidance (IVDD 98/79/EC) or corresponding international regulations before launch. more

• Interference and HAMA problems
  

  Immunoassays are bioanalytical methods based on antibodies. These include ELISA, EIA, RIA, Western blotting, protein arrays, lateral flow assays (immuno-chromatography), immunohistochemistry or immuno-PCR. Antibodies detect the substances (analytes) in immunoassays. This detection is always highly specific and only the analytes are detected and bound. This is the theory! Practically any antibody not only binds its analyte. It also binds several other substances, but with very different affinities. more

• Half a Century of Chromatography with Agilent and Predecessors
  

  Twsett originated the chromatography with his work about the separation of chlorophyll in 1903. For some time it was relatively quite around this new technology. Exceptions were the workings of Kuhn and Lederer (1931) as well as of Hesse (1936 and 1942). A break through succeeded to E. Cremer during the 40ies, but hardly considered caused by the war events, what however in the years 1950/51 by the conception of the gas chromatography suddenly changed and involved a rapid development more

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