Telomerase

News Telomerase

• Telomerase gene therapy slows ageing, improves health in mice

  Gene therapy allows older mice to live longer, healthier lives report researchers in a new study published in EMBO Molecular Medicine. Mice that received a single gene-therapy treatment to deliver telomerase to different cells in the body showed drastic improvements in health, fitness and longevity. more

• A double ring ceremony prepares telomerase RNA to wed its protein partner
  

  Few molecules are more interesting than DNA — except of course RNA. After two decades of research, that "other macromolecule" is no longer considered a mere messenger between glamorous DNA and protein-synthesizing machines. We now know that RNA has been leading a secret life, regulating gene express more

• BGU researchers make scientific breakthrough in the fight against neurodegenerative diseases

  A patented breakthrough treatment for neurodegenerative diseases has secured over $1 million. Prof. Esther Priel of Ben-Gurion University and her colleagues Prof. Aviv Gazit (formerly of Hebrew University) and Prof. Shimon Slavin (also formerly of Hebrew University and now director of the Internatio more

White papers Telomerase

• Nobel Prize for Solving the End-Replication Problem
  

  The Nobel Assembly awarded this year's Nobel Prize in Medicine to Elizabeth H. Blackburn, Jack W. Szostak, and Carol W. Greider for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase. With their ingenious genetic research and meticulous biochemical studies, they not only solved a fundamental problem in biology but also opened a new field of research and initiated the development of potential therapies against disease more

Publications Telomerase

• Identification of purple sea urchin telomerase RNA using a next-generation sequencing based approach [METHOD]

  Telomerase is a ribonucleoprotein (RNP) enzyme essential for telomere maintenance and chromosome stability. While the catalytic telomerase reverse transcriptase (TERT) protein is well conserved across eukaryotes, telomerase RNA (TR) is extensively divergent in size, sequence, and structure. This di more

• HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment

  The EMBO Journal. doi:10.1038/emboj.2013.105 Authors: Dennis Kappei, Falk Butter, Christian Benda, Marion Scheibe, Irena Draškovič, Michelle Stevense, Clara Lopes Novo, Claire Basquin, Masatake Araki, Kimi Araki, Dragomir Blazhev Krastev, Ralf Kittler, Rolf Jessberger, J Arturo Lon more

• It's getting HOT at telomeres

  The EMBO Journal. doi:10.1038/emboj.2013.119 Author: Madalena Tarsounas EMBO J advance online publication, 17 May 2013; doi:10.1038/emboj.2013105How telomerase and telomeres are brought together to alleviate telomere shortening and preserve genome integrity in the cell remains in more

Market studies Telomerase

• Vanguard Pharmaceutical Corporation - Strategic SWOT Analysis Review

  Vanguard Pharmaceutical Corporation (Vanguard) is engaged in research, development, manufacture, and sale of generic and oncology pharmaceuticals. It principally offers haematological and supportive care drugs to cure cancer. The company's product portfolio comprises antibiotics, antibacterial, anti more

• Vanguard Pharmaceutical Corporation (VGPH) - Strategic SWOT Analysis Review

  Vanguard Pharmaceutical Corporation (Vanguard) is engaged in research, development, manufacture, and sale of generic and oncology pharmaceuticals. It principally offers haematological and supportive care drugs to cure cancer. The company's product portfolio comprises antibiotics, antibacterial, anti more

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