Systemic Lupus Erythematosus

News Systemic Lupus Erythematosus

• A genetic accelerator hits the gas on autoimmune diseases

  A "genetic accelerator" is responsible for the most severe cases of Lupus (systemic lupus erythemathosus), an autoimmune disease: the accelerator, called enhancer HS1.2, speeds up the activity of some critical genes of the immune system involved in the disease.A team of Italian researchers at the Ca more

• Epratuzumab phase IIb data show pipeline drug had positive effect in patients suffering from systemic lupus erythematosus

  UCB and U.S. based partner Immunomedics Inc.announced that results from the phase IIB study, EMBLEM™, showed that certain doses of epratuzumab were associated with a meaningful and statistically significant reduction in disease activity in adult patients with moderate to severe active SLE. The EMBL more

• Karus Therapeutics Commences Preclinical Development of Novel Immune and Inflammation Programmes

  Karus Therapeutics Ltd has commenced preclinical development of its HDAC6 and PI3-Kinase inhibitor programmes for the treatment of immune and inflammatory diseases such as rheumatoid arthritis (RA). Karus aims to initiate clinical trials for both programmes in 2011. Karus’s highly potent and selec more

Publications Systemic Lupus Erythematosus

• The Impact of Genetic Susceptibility to Systemic Lupus Erythematosus on Placental Malaria in Mice

  by Michael Waisberg, Christina K. Lin, Chiung-Yu Huang, Mirna Pena, Marlene Orandle, Silvia Bolland, Susan K. Pierce Severe malaria, including cerebral malaria (CM) and placental malaria (PM), have been recognized to have many of the features of uncontrolled inflammation. We recently showed that more

• Association of P2X7R gene polymorphisms with systemic lupus erythematosus in a Chinese population

  The P2X7 receptor is a ligand-gated cationic channel receptor that is actived by ATP and normally expressed by a variety of immune system cells, including macrophages and lymphocytes. Because it leads to release of IL-1β and cell death by apoptosis or necrosis, it is a potential therapeutic target more

• Vitamins and systemic lupus erythematosus: to D or not to D

  Expert Review of Clinical Immunology , May 2013, Vol. 9, No. 5, Pages 397-399. more

Market studies Systemic Lupus Erythematosus

• Systemic Lupus Erythematosus Global Clinical Trials Review, H1, 2012

  Introduction GlobalData's clinical trial report, “Systemic Lupus Erythematosus Global Clinical Trials Review, H1, 2012" provides data on the Systemic Lupus Erythematosus clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Systemic Lupus Er more

• Systemic Lupus Erythematosus – Pipeline Review, H2 2012

  Introduction Global Markets Direct’s, 'Systemic Lupus Erythematosus - Pipeline Review, H2 2012', provides an overview of the Systemic Lupus Erythematosus therapeutic pipeline. This report provides information on the therapeutic development for Systemic Lupus Erythematosus, complete with latest upd more

• Systemic Lupus Erythematosus – Pipeline Review, H1 2012

  Introduction Global Markets Direct’s, 'Systemic Lupus Erythematosus - Pipeline Review, H1 2012', provides an overview of the Systemic Lupus Erythematosus therapeutic pipeline. This report provides information on the therapeutic development for Systemic Lupus Erythematosus, complete with latest upd more

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