StemCells

News StemCells

• Cardio3 BioSciences Announces Results of the C-Cure Phase II Clinical Trial

  Cardio3 BioSciences presented detailed data from the Phase II clinical trial of C3BS-CQR-1 (C-Cure®), its novel stem cell therapy for ischemic cardiomyopathy, at the 60th annual American College of Cardiology in New Orleans, USA.The data were presented by Dr. Jozef Bartunek, Associate Director of th more

• Reprogrammed stem cells hit a roadblock

  It's a discordant note in the symphony of good news that usually accompanies stem cell research announcements. Stem cells hold enormous promise in regenerative medicine, thanks to their ability to regenerate diseased or damaged tissues. They have made it possible to markedly improve the effectivenes more

• Tracking stem cells after transplantation

  Stable nanoparticles that could be used to track the fate of neural stem cells following transplantation in the spinal chord have been developed by UK scientists. The cells are a promising treatment for repairing spinal chord injuries as they have the ability to generate tissue. Magnetic resonance i more

White papers StemCells

• HelpCorner - Gene Silencing
  

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• Array Capture-mediated Resequencing Leads to the Discovery of Four Novel Mutations in the Mouse
  

  By using array-based sequence capture and pyrosequencing to sequence an allelic series from the classically defined Kit locus (~200 kb) from each of five noncomplementing Kit mutants (one known allele and four unknown alleles), D'Ascenzo and co-workers discovered and validated a nonsynonymous coding mutation for each allele. These data represent the first documentation and confirmation of the fact that the new technologies can be used to efficiently discover causative mutations. Importantly, these results also provide the framework for constructing the efficient detection of causative mutations in mutant mouse strains moving forward. The standards presented here, coupled with the latest sequence capture methods (e.g., whole-exome arrays or solution-based methods) and next-generation sequencing technologies, promise to signicantly close the gap between phenotype and genotype in the mouse more

• HelpCorner - Transfection
  

  Transfection is the delivery of DNA, RNA, proteins, and macromelecules into eukaryotic cells. The goals for transfection include the study of gene function and regulation as well as protein expression and function. It is also used for gene silencing and protein production. According to the application, the information can be either transiently (transient transfection) or permanently expressed (stable transfection). Based on the strategies, the transfection methods can be divided into three groups: more

Publications StemCells

• GPAT2, a mitochondrial outer membrane protein, in piRNA biogenesis in germline stem cells [ARTICLES]

  piRNA (PIWI-interacting RNA) is a germ cell–specific small RNA in which biogenesis PIWI (P-element wimpy testis) family proteins play crucial roles. MILI (mouse Piwi-like), one of the three mouse PIWI family members, is indispensable for piRNA production, DNA methylation of retrotransposons presuma more

• Editors' Choice

  Geophysics: Hawaii's Deep Plumbing System | Economics: A Look at the Data | Pathogens: The End of Antiquity | Chemistry: UN Coaxed to Neutrality | Chemistry: Shepherding Stem Cells | Physics: Spin Thermometers | Developmental Biology: Putting on the Brakes more

• [News & Analysis] Biomedicine: Human Stem Cells From Cloning, Finally

  This time it looks like it's for real: Researchers have made personalized human embryonic stem cells with a method similar to how Dolly the sheep was cloned—though with an added jolt of caffeine. more

Market studies StemCells

• Epigenetics R&D Pipeline - Histone Deacetylases (HDACs) Offer the Most Promising Targets and Outnumber Other Classes of Epigenetic Targets

  GBI Research, a leading business intelligence provider, has released its latest research, entitled “Epigenetics R&D Pipeline - Histone Deacetylases (HDACs) Offer the Most Promising Targets and Outnumber Other Classes of Epigenetic Targets”. The report is built using data and information sourced from more

• Translational Regenerative Medicine - Oncology, CNS and Cardiovascular-Rich Pipeline Features Innovative Stem Cell and Gene Therapy Applications

  GBI Research, the leading business intelligence provider, has released its latest research, “Translational Regenerative Medicine - Oncology, CNS and Cardiovascular-Rich Pipeline Features Innovative Stem Cell and Gene Therapy Applications”, which provides insights into the global regenerative medicin more

• Thailand Pharmaceuticals and Healthcare Report Q3 2012

  BMI View: Usage of compulsory licenses, low-capita healthcare expenditure, widespread corruption and general regulatory lapses will continue to deter investments from foreign pharmaceutical companies. This is especially so when BMI is witnessing strong growth and increased government commitment to more

Websites StemCells