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• Genetic causes of canine mammary tumors

  Various forms of cancer are one of the most common causes of death in dogs today. But both diagnosis and methods of treatment for cancer in dogs and cats have developed dramatically in recent years. In his doctoral dissertation at SLU, the Swedish University of Agricultural Sciences in Sweden, veter more

White papers Springer

• Molecular Probes® NanoOrange® Assay Performed on BMG LABTECH FLUOstar OPTIMA Microplate Reader
  

  The field of proteomics has expanded dramatically in recent years with research on a whole host of organisms. Techniques such as two dimensional difference gel electrophoresis (2D DIGE) require the accurate quantitation of protein, as up to three labelled samples can be loaded on a single gel for comparison. Assay methods for determining protein quantitation include absorbance at 280 nm(1), the Bradford assay(2), Lowry assay(3), BCA method(4) and more sensitive assays such as Fluoroprofile® (Sigma-Aldrich) and NanoOrange® (Molecular Probes®)5(). more

Publications Springer

• Rod Monochromacy and the Coevolution of Cetacean Retinal Opsins

  by Robert W. Meredith, John Gatesy, Christopher A. Emerling, Vincent M. York, Mark S. Springer Cetaceans have a long history of commitment to a fully aquatic lifestyle that extends back to the Eocene. Extant species have evolved a spectacular array of adaptations in conjunction with their deploym more

• Reply to Gatesy and Springer: The multispecies coalescent model can effectively handle recombination and gene tree heterogeneity [Biological Sciences]

  Gatesy and Springer (1) suggest that coalescent methods cannot build a reliable phylogeny from gene trees, particularly from exonic sequences concatenated in silico. However, the authors confuse several key issues in coalescent theory and phylogenetic reconstruction, and their criticisms are unfound more

• Duplicate Abalone Egg Coat Proteins Bind Sperm Lysin Similarly, but Evolve Oppositely, Consistent with Molecular Mimicry at Fertilization

  by Jan E. Aagaard, Stevan A. Springer, Scott D. Soelberg, Willie J. Swanson Sperm and egg proteins constitute a remarkable paradigm in evolutionary biology: despite their fundamental role in mediating fertilization (suggesting stasis), some of these molecules are among the most rapidly ev more

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