Respiratory Disease

News Respiratory Disease

• Study outlines risk factors for poor outcome, mortality following hip fracture

  A new study identifies predictors of complications and mortality following a hip fracture, including dialysis, cardiac disease, diabetes, and a longer time before surgery – the only modifiable risk factor when patients are hospitalized. Each year, more than 340,000 Americans are hospitalized for hip more

• Ablynx announces an extension of its global strategic nanobody alliance with Boehringer Ingelheim

  Ablynx announced a two-year extension of the initial five-year research funding by Boehringer Ingelheim of their global strategic alliance to discover, develop and commercialise up to 10 different Nanobody® therapeutics. The extension which will run until September 2014, will allow all the existing more

• BioFocus and Argenta Announce Drug Discovery Collaboration with AstraZeneca in Respiratory and Inflammatory Disease

  Galapagos’ service companies, BioFocus and Argenta, announced they have entered into a multi-year collaboration agreement with AstraZeneca to find new compounds against key targets of interest to AstraZeneca’s research programs in respiratory and inflammatory diseases. Under the terms of the collabo more

White papers Respiratory Disease

• Orphan Drugs – An Alternative to the declining Blockbuster Model?
  

  Up until the new millennium, the pharmaceutical industry grew stronger by 11%. However, the blockbuster model is increasingly at risk and the declining growth rates in the industry require a search for new strategies. In this context, orphan drugs are becoming increasingly important more

Publications Respiratory Disease

• The Coexistence of Asthma and Chronic Obstructive Pulmonary Disease (COPD): Prevalence and Risk Factors in Young, Middle-aged and Elderly People from the General Population

  by Roberto de Marco, Giancarlo Pesce, Alessandro Marcon, Simone Accordini, Leonardo Antonicelli, Massimiliano Bugiani, Lucio Casali, Marcello Ferrari, Gabriele Nicolini, Maria Grazia Panico, Pietro Pirina, Maria Elisabetta Zanolin, Isa Cerveri, Giuseppe Verlato Background The joint distribution o more

• Src Homology 2‐containing Protein Tyrosine Phosphatase (SHP‐2) acts as a negative regulator for MUC5AC transcription via the inhibition of the ERK1/2 MAPK signaling pathway in ...

  Abstract Aims Mucus hypersecretion has been frequently observed in inflammation respiratory diseases. However, the negative regulators for mucus overproduction have not been readily identified. Our work focused on identifying novel negative regulator that modulates mucus overproduction in the more

• Type I IFN Triggers RIG-I/TLR3/NLRP3-dependent Inflammasome Activation in Influenza A Virus Infected Cells

  by Julien Pothlichet, Isabelle Meunier, Beckley K. Davis, Jenny P-Y. Ting, Emil Skamene, Veronika von Messling, Silvia M. Vidal Influenza A virus (IAV) triggers a contagious and potentially lethal respiratory disease. A protective IL-1β response is mediated by innate receptors in macropha more

Market studies Respiratory Disease

• Innovations in Drug Delivery - Broad-based Proprietary Technology Platforms to Address Delivery Efficiency and Improve Patient Compliance

  GBI Research, the leading business intelligence provider, has released its latest research, “Innovations in Drug Delivery - Broad-based Proprietary Technology Platforms to Address Delivery Efficiency and Improve Patient Compliance”. The report provides an overview of the most exciting innovations in more

• Pharmaceutical Leaders 2012 - Key Trends, Emerging Strategies and Financial Analysis of the Top Performers

  Introduction GlobalData’s “Pharmaceutical Leaders 2012 - Key Trends, Emerging Strategies and Financial Analysis of the Top Performers” Report integrates deep research of top players in the pharmaceutical industry with our proprietary analysis and ranking methodology to reveal top performers, indus more

• Chile Pharmaceuticals and Healthcare Report Q4 2012

  BMI View: Pharmaceutical companies will continue to look to fast growing emerging markets for revenue growth, and we believe that Latin American economies, with rising incomes, ageing populations and increased spending on healthcare will provide significant opportunities. Indeed, it is our view that more

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